ESM-DBP

Closed weights Hunan University 650M parameters September 2024

No estimate

No hardware requirements for this model

The weights for this model have not been published, so it cannot be downloaded or run on your own hardware at any size. It is reachable only through its provider, and no graphics card changes that.

On record

Full specification

Everything on record for this model. Most of it describes how it was trained rather than how it runs — useful context for judging how much work went into it, and how it compares with models built at a different scale.

Origin

Who built this model, where, and when it was published.

Organisation
Hunan University
Organisation type
Academia
Country
China
Published
7 September 2024
Authors
Wenwu Zeng, Yutao Dou, Liangrui Pan, Liwen Xu, Shaoliang Peng

What it does

The problem areas the model was built for. A model can carry several of each.

Domain
Biology
Task
Protein or nucleotide language model (pLM/nLM)
Base model
ESM2-650M

Size

How large the model is and how much data it was trained on. Parameters are the figure that decides whether it fits on a given graphics card.

Parameters
650M

"so the ESM2 model with 650 million parameters is used to continue training here."

Training data
7,661,880 tokens

"170,264 non-redundant DBP sequences (abbreviate as UniDBP40) are used as the pretraining data set."

Batch size
100

"The batch size is set to 100."

Training compute

The arithmetic performed to train the model, measured in floating-point operations. It is a measure of what the training run cost, not of how fast the finished model answers you.

Fine-tuning compute
1.3 × 10¹⁹ FLOP

"The model is trained for approximately 51k steps and took about 3 days on four Tesla V100 GPUs with 16 G memory." Assume FP16 precision and 40% utilization.

The training run

What it physically took to train: which chips, how many, for how long, and what that drew from the wall.

Chips used
4
Wall-clock time
72 hours

"The model is trained for approximately 51k steps and took about 3 days on four Tesla V100 GPUs with 16 G memory."

How it is classified

Labels the source dataset applies when tracking notable models, and how confident it is in the entry.

Record confidence
Confident

Sources

Where this record came from and when it was last checked.

Reference
Improving prediction performance of general protein language model by domain-adaptive pretraining on DNA-binding protein
Last updated
28 November 2025

What the numbers mean

What this model is

ESM-DBP was published by Hunan University, in China, in September 2024. The organisation is categorised as academia.

It works in Biology, and is recorded as doing protein or nucleotide language model (pLM/nLM).

Its starting point was ESM2-650M — most models at this scale are adapted from an existing base rather than built from nothing.

Its weights were never published, so it can only be reached through its provider. No graphics card changes that.

What went into building it

The training set ran to roughly 7,661,880 tokens.

Answers

ESM-DBP — common questions

01

What is ESM-DBP used for?

ESM-DBP works in Biology, and is recorded as handling protein or nucleotide language model (pLM/nLM). These are the areas it was designed around; they describe intent rather than a hard boundary.

02

What GPU do I need to run ESM-DBP?

None. ESM-DBP is a closed model — its weights were never published, so it cannot be downloaded or run on your own hardware at any price. It is reachable only through its provider.

03

Is ESM-DBP open source?

The licensing for ESM-DBP was never recorded in our source data. We treat unstated licensing as closed, because an unrecorded licence is not one to rely on.

04

How many parameters does ESM-DBP have?

ESM-DBP has 650M parameters. "so the ESM2 model with 650 million parameters is used to continue training here.". That figure is the total, and it is what decides how much memory the model needs — roughly half a gigabyte per billion at the compression most people use.

05

Who created ESM-DBP?

ESM-DBP was published by Hunan University, based in China, categorised as academia.

06

When was ESM-DBP released?

ESM-DBP was published in September 2024. Capability per parameter has improved considerably since, so a newer model of the same size is often the better use of the same hardware.

Source

Original publication

Record last updated 28 November 2025

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