HelixFold3

Closed weights Tecorigin LTD,Tsinghua University,Baidu August 2024

No estimate

No hardware requirements for this model

The weights for this model have not been published, so it cannot be downloaded or run on your own hardware at any size. It is reachable only through its provider, and no graphics card changes that.

On record

Full specification

Everything on record for this model. Most of it describes how it was trained rather than how it runs — useful context for judging how much work went into it, and how it compares with models built at a different scale.

Origin

Who built this model, where, and when it was published.

Organisation
Tecorigin LTD,Tsinghua University,Baidu
Organisation type
Industry,Academia,Industry
Country
China
Published
30 August 2024
Authors
Lihang Liu, Shanzhuo Zhang, Yang Xue, Xianbin Ye, Kunrui Zhu, Yuxin Li, Yang Liu, Wenlai Zhao, Hongkun Yu, Zhihua Wu, Xiaonan Zhang, Xiaomin Fang

What it does

The problem areas the model was built for. A model can carry several of each.

Domain
Biology
Task
Protein folding prediction, Protein interaction prediction, Protein nucleotide interaction prediction, RNA-Protein interaction prediction, Protein design, Drug discovery

Size

How large the model is and how much data it was trained on. Parameters are the figure that decides whether it fits on a given graphics card.

Training data
tokens

Availability

Whether you can obtain the model and run it on your own hardware, which is what decides if any of the graphics-card figures on this page apply.

Weights
Closed — provider access only
Model access
API access
Training code
Open (non-commercial)

https://paddlehelix.baidu.com/ https://paddlehelix.baidu.com/app/tut/guide/all/helixfold3sdk CC BY-NC-SA 4.0 https://github.com/PaddlePaddle/PaddleHelix

How it is classified

Labels the source dataset applies when tracking notable models, and how confident it is in the entry.

Record confidence
Unknown

Sources

Where this record came from and when it was last checked.

Reference
Technical Report of HelixFold3 for Biomolecular Structure Prediction
Last updated
28 November 2025

What the numbers mean

Where it came from

HelixFold3 was published by Tecorigin LTD,Tsinghua University,Baidu, in the country recorded as China, during August 2024. The publishing organisation is categorised as industry,Academia,Industry.

It works in the domain of Biology, and is recorded as performing the task of protein folding prediction, Protein interaction prediction, Protein nucleotide interaction prediction, RNA-Protein interaction prediction, Protein design, Drug discovery.

Its weights were never published, so it can only be reached through its provider. No graphics card changes that.

Answers

HelixFold3 — common questions

01

HelixFold3— what is it used for?

It works in the domain of Biology, and is recorded as handling the task of protein folding prediction, Protein interaction prediction, Protein nucleotide interaction prediction, RNA-Protein interaction prediction, Protein design, Drug discovery. A model can carry several of each, so these are the areas it was built for rather than a limit on what it will attempt.

02

HelixFold3— what GPU do I need to run it?

None. This is a closed model — its weights were never published, so it cannot be downloaded or run on your own hardware at any price. It is reachable only through its provider.

03

HelixFold3— is it open source?

No. Its weights have not been published, so it exists only as a service controlled by its owner.

04

HelixFold3— how many parameters does it have?

No parameter count has been published for it, which is why no memory or speed figure appears on this page.

05

HelixFold3— who created it?

It was published by Tecorigin LTD,Tsinghua University,Baidu, based in China, an organisation categorised as industry,Academia,Industry.

06

HelixFold3— when was it released?

It was published in August 2024. Capability per parameter has improved considerably since, so a newer model of the same size is often the better use of the same hardware.

Source

Original publication

Record last updated 28 November 2025

The other direction

Looking at it from the other side?

This page starts from the model. If you already own a card and want to know everything it will run, start from the hardware instead.