RENNAISSANCE

Open weights Ecole Polytechnique F´ed´erale de Lausanne (EPFL),University of Cambridge,Harvard Medical School August 2024

No estimate

No hardware requirements for this model

This model's weights are open, but no parameter count has been published for it. Every memory and speed figure starts from that number, so we would rather show nothing than a fabricated estimate.

On record

Full specification

Everything on record for this model. Most of it describes how it was trained rather than how it runs — useful context for judging how much work went into it, and how it compares with models built at a different scale.

Origin

Who built this model, where, and when it was published.

Organisation
Ecole Polytechnique F´ed´erale de Lausanne (EPFL),University of Cambridge,Harvard Medical School
Organisation type
Academia,Academia,Academia
Country
Switzerland, United Kingdom of Great Britain and Northern Ireland, United States of America
Published
30 August 2024
Authors
Subham Choudhury, Bharath Narayanan, Michael Moret, Vassily Hatzimanikatis, Ljubisa Miskovic

What it does

The problem areas the model was built for. A model can carry several of each.

Domain
Biology
Task
Cell Biology

Size

How large the model is and how much data it was trained on. Parameters are the figure that decides whether it fits on a given graphics card.

Training data
tokens

"a machine learning framework that efficiently parameterizes biologically relevant kinetic models of metabolism without requiring training data."

Availability

Whether you can obtain the model and run it on your own hardware, which is what decides if any of the graphics-card figures on this page apply.

Weights
Open — downloadable
Model access
Open weights (unrestricted)
Training code
Open source

Code availability A Python implementation of the RENAISSANCE workflow is publicly available via GitHub at https://github.com/EPFL-LCSB/renaissance (apache 2.0) and https://gitlab.com/EPFL-LCSB/renaissance. The ORACLE framework is implemented in the SKimPy (Symbolic Kinetic models in Python) toolbox, available via GitHub at https://github.com/EPFL-LCSB/skimpy Creative Commons Attribution 4.0 International for weights https://zenodo.org/records/7930002

How it is classified

Labels the source dataset applies when tracking notable models, and how confident it is in the entry.

Record confidence
Unknown
Citations
10

Sources

Where this record came from and when it was last checked.

Reference
Generative machine learning produces kinetic models that accurately characterize intracellular metabolic states
Last updated
28 November 2025

What the numbers mean

What this model is

RENNAISSANCE was published by Ecole Polytechnique F´ed´erale de Lausanne (EPFL),University of Cambridge,Harvard Medical School, in the country recorded as Switzerland, during August 2024. The category the publisher falls under is academia,Academia,Academia.

It works in the domain of Biology, and is recorded as performing the task of cell Biology.

The weights are published, so it can be downloaded and run on your own hardware indefinitely, offline, with no account attached.

Answers

RENNAISSANCE — common questions

01

RENNAISSANCE— how many parameters does it have?

No parameter count has been published for it, which is why no memory or speed figure appears on this page.

02

RENNAISSANCE— who created it?

It was published by Ecole Polytechnique F´ed´erale de Lausanne (EPFL),University of Cambridge,Harvard Medical School, based in Switzerland, an organisation categorised as academia,Academia,Academia.

03

RENNAISSANCE— when was it released?

It was published in August 2024. Capability per parameter has improved considerably since, so a newer model of the same size is often the better use of the same hardware.

04

RENNAISSANCE— what is it used for?

It works in the domain of Biology, and is recorded as handling the task of cell Biology. Models frequently carry more than one of each, and the tags describe purpose rather than capability limits.

05

RENNAISSANCE— where can I download it?

The weights are published, though we do not hold a repository link for it. This site calculates hardware requirements rather than hosting model files.

06

RENNAISSANCE— what GPU do I need to run it?

We cannot say. It has open weights, but no parameter count has been published for it, and every memory and speed calculation starts from that number. We would rather show nothing than a fabricated estimate.

07

RENNAISSANCE— is it open source?

Its weights are published, so it can be downloaded and run on your own hardware. Note that open weights is not the same as open source in the full sense — it says nothing about the training data, the training code, or the commercial terms attached.

Source

Original publication

Record last updated 28 November 2025

The other direction

Looking at it from the other side?

This page starts from the model. If you already own a card and want to know everything it will run, start from the hardware instead.