ProteinReDiff

Open weights FPT Software AI Center,University of Chicago,Indiana State University June 2024

No estimate

No hardware requirements for this model

This model's weights are open, but no parameter count has been published for it. Every memory and speed figure starts from that number, so we would rather show nothing than a fabricated estimate.

On record

Full specification

Everything on record for this model. Most of it describes how it was trained rather than how it runs — useful context for judging how much work went into it, and how it compares with models built at a different scale.

Origin

Who built this model, where, and when it was published.

Organisation
FPT Software AI Center,University of Chicago,Indiana State University
Organisation type
Industry,Academia
Country
Vietnam, United States of America
Published
12 June 2024
Authors
Viet Thanh Duy Nguyen, Nhan D. Nguyen, Truong Son Hy

What it does

The problem areas the model was built for. A model can carry several of each.

Domain
Biology
Task
Protein design

Size

How large the model is and how much data it was trained on. Parameters are the figure that decides whether it fits on a given graphics card.

Training data
tokens

Total Samples: 9,430 (PDBBind) + 15,261 (CATH) = 24,691 samples Tokens per Sample: 300 (protein) + 50 (SMILES) = 350 tokens Total Data Points: 24,691 × 350 = 8,641,850

Epochs
100

Availability

Whether you can obtain the model and run it on your own hardware, which is what decides if any of the graphics-card figures on this page apply.

Weights
Open — downloadable
Model access
Open weights (unrestricted)
Training code
Open source

MIT license for weights, training and inference code https://github.com/HySonLab/Protein_Redesign

How it is classified

Labels the source dataset applies when tracking notable models, and how confident it is in the entry.

Record confidence
Confident
Citations
2

Sources

Where this record came from and when it was last checked.

Reference
Complex-based Ligand-Binding Proteins Redesign by Equivariant Diffusion-based Generative Models
Last updated
28 November 2025

What the numbers mean

Background

ProteinReDiff was published by FPT Software AI Center,University of Chicago,Indiana State University, in Vietnam, in June 2024. The organisation is categorised as industry,Academia.

It works in Biology, and is recorded as doing protein design.

Because its weights were released, nothing about running it depends on a provider staying available — it is yours once downloaded.

Answers

ProteinReDiff — common questions

01

Is ProteinReDiff open source?

Its weights are published, so ProteinReDiff can be downloaded and run on your own hardware. Note that open weights is not the same as open source in the full sense — it says nothing about the training data, the training code, or the commercial terms attached.

02

How many parameters does ProteinReDiff have?

No parameter count has been published for ProteinReDiff, which is why no memory or speed figure appears on this page.

03

Who created ProteinReDiff?

ProteinReDiff was published by FPT Software AI Center,University of Chicago,Indiana State University, based in Vietnam, categorised as industry,Academia.

04

When was ProteinReDiff released?

ProteinReDiff was published in June 2024. Capability per parameter has improved considerably since, so a newer model of the same size is often the better use of the same hardware.

05

What is ProteinReDiff used for?

ProteinReDiff works in Biology, and is recorded as handling protein design. Models frequently carry more than one of each, and the tags describe purpose rather than capability limits.

06

Where can I download ProteinReDiff?

The weights for ProteinReDiff are published, though we do not hold a repository link for it. This site calculates hardware requirements rather than hosting model files.

07

What GPU do I need to run ProteinReDiff?

We cannot say. ProteinReDiff has open weights, but no parameter count has been published for it, and every memory and speed calculation starts from that number. We would rather show nothing than a fabricated estimate.

Source

Original publication

Record last updated 28 November 2025

The other direction

Looking at it from the other side?

This page starts from the model. If you already own a card and want to know everything it will run, start from the hardware instead.