Prot2Token

Closed weights University of Missouri,Politecnico di Milano 650M parameters June 2024

No estimate

No hardware requirements for this model

The weights for this model have not been published, so it cannot be downloaded or run on your own hardware at any size. It is reachable only through its provider, and no graphics card changes that.

On record

Full specification

Everything on record for this model. Most of it describes how it was trained rather than how it runs — useful context for judging how much work went into it, and how it compares with models built at a different scale.

Origin

Who built this model, where, and when it was published.

Organisation
University of Missouri,Politecnico di Milano
Organisation type
Academia
Country
United States of America, Italy
Published
3 June 2024
Authors
Mahdi Pourmirzaei, Farzaneh Esmaili, Mohammadreza Pourmirzaei, Duolin Wang, Dong Xu

What it does

The problem areas the model was built for. A model can carry several of each.

Domain
Biology
Task
Protein or nucleotide language model (pLM/nLM)
Base model
ESM2-650M

Size

How large the model is and how much data it was trained on. Parameters are the figure that decides whether it fits on a given graphics card.

Parameters
650M
Training data
tokens

1,024,055 = 8,678 + 53,571 + 21,446 + 15,550 + 29,898 + 12,312 + 29,215 + 23,604 + 35,669 + 8,716 + 300,700 + 6,391 + 16,436 + 22,841 + 10,400 + 428,628 307,216,500 = 1,024,055 × 300 Final estimate: 3.1 × 10⁸

Epochs
16

How it is classified

Labels the source dataset applies when tracking notable models, and how confident it is in the entry.

Record confidence
Confident
Citations
10

Sources

Where this record came from and when it was last checked.

Reference
Prot2Token: A multi-task framework for protein language processing using autoregressive language modeling
Last updated
28 November 2025

What the numbers mean

Where it came from

Prot2Token was published by University of Missouri,Politecnico di Milano, in United States of America, in June 2024. academia is the category the publisher falls under.

It works in Biology, and is recorded as doing protein or nucleotide language model (pLM/nLM).

It builds on ESM2-650M, which is why it shares that model's general shape and size.

This is a closed model: the trained values stayed with whoever produced them, and there is no local version to run.

Answers

Prot2Token — common questions

01

Is Prot2Token open source?

The licensing for Prot2Token was never recorded in our source data. We treat unstated licensing as closed, because an unrecorded licence is not one to rely on.

02

How many parameters does Prot2Token have?

Prot2Token has 650M parameters. That figure is the total, and it is what decides how much memory the model needs — roughly half a gigabyte per billion at the compression most people use.

03

Who created Prot2Token?

Prot2Token was published by University of Missouri,Politecnico di Milano, based in United States of America, categorised as academia.

04

When was Prot2Token released?

Prot2Token was published in June 2024. Capability per parameter has improved considerably since, so a newer model of the same size is often the better use of the same hardware.

05

What is Prot2Token used for?

Prot2Token works in Biology, and is recorded as handling protein or nucleotide language model (pLM/nLM). These are the areas it was designed around; they describe intent rather than a hard boundary.

06

What GPU do I need to run Prot2Token?

None. Prot2Token is a closed model — its weights were never published, so it cannot be downloaded or run on your own hardware at any price. It is reachable only through its provider.

Source

Original publication

Record last updated 28 November 2025

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