ProSST

Closed weights Shanghai Jiao Tong University,Shanghai AI Lab,East China University of Science and Technology 110M parameters May 2024

No estimate

No hardware requirements for this model

The weights for this model have not been published, so it cannot be downloaded or run on your own hardware at any size. It is reachable only through its provider, and no graphics card changes that.

On record

Full specification

Everything on record for this model. Most of it describes how it was trained rather than how it runs — useful context for judging how much work went into it, and how it compares with models built at a different scale.

Origin

Who built this model, where, and when it was published.

Organisation
Shanghai Jiao Tong University,Shanghai AI Lab,East China University of Science and Technology
Organisation type
Academia,Academia,Academia
Country
China
Published
17 May 2024
Authors
Mingchen Li, Pan Tan, Xinzhu Ma, Bozitao Zhong, Huiqun Yu, Ziyi Zhou, Wanli Ouyang, Bingxin Zhou, Liang Hong, Yang Tan

What it does

The problem areas the model was built for. A model can carry several of each.

Domain
Biology
Task
Protein or nucleotide language model (pLM/nLM)

Size

How large the model is and how much data it was trained on. Parameters are the figure that decides whether it fits on a given graphics card.

Parameters
110M

Explicitly denoted in Table 2

Training data
tokens

18.8M structures × 300 residues per structure = 5.64B data points ≈ 5.6B data points

Training compute

The arithmetic performed to train the model, measured in floating-point operations. It is a measure of what the training run cost, not of how fast the finished model answers you.

Training compute
6.5 × 10²⁰ FLOP

"All ProSST models is trained on a DGX-A800 GPU (8×80G) server in BF16 precision for about a month." 8*77970000000000*0.4*1month=646714368000000000000

How it was established
Hardware

The training run

What it physically took to train: which chips, how many, for how long, and what that drew from the wall.

Training hardware
NVIDIA A800 PCIe 40 GB
Chips used
8
Wall-clock time
720 hours (30 days)

"All ProSST models is trained [...] for about a month."

Power draw
4.0 kW

How it is classified

Labels the source dataset applies when tracking notable models, and how confident it is in the entry.

Record confidence
Confident
Citations
57

Sources

Where this record came from and when it was last checked.

Reference
ProSST: Protein Language Modeling with Quantized Structure and Disentangled Attention
Last updated
1 January 2026

What the numbers mean

What this model is

ProSST was published by Shanghai Jiao Tong University,Shanghai AI Lab,East China University of Science and Technology, in China, in May 2024. The organisation is categorised as academia,Academia,Academia.

It works in Biology, and is recorded as doing protein or nucleotide language model (pLM/nLM).

Its weights were never published, so it can only be reached through its provider. No graphics card changes that.

Training and provenance

Producing it required around 6.5 × 10²⁰ FLOP of arithmetic, on NVIDIA A800 PCIe 40 GB, which is a statement about the training budget rather than about inference.

Answers

ProSST — common questions

01

What is ProSST used for?

ProSST works in Biology, and is recorded as handling protein or nucleotide language model (pLM/nLM). These are the areas it was designed around; they describe intent rather than a hard boundary.

02

How much compute was used to train ProSST?

Around 6.5 × 10²⁰ FLOP, on NVIDIA A800 PCIe 40 GB. That measures what producing the model cost and says nothing about how quickly it answers once trained — inference speed comes from memory bandwidth, not from the training budget.

03

What GPU do I need to run ProSST?

None. ProSST is a closed model — its weights were never published, so it cannot be downloaded or run on your own hardware at any price. It is reachable only through its provider.

04

Is ProSST open source?

The licensing for ProSST was never recorded in our source data. We treat unstated licensing as closed, because an unrecorded licence is not one to rely on.

05

How many parameters does ProSST have?

ProSST has 110M parameters. Explicitly denoted in Table 2. That figure is the total, and it is what decides how much memory the model needs — roughly half a gigabyte per billion at the compression most people use.

06

Who created ProSST?

ProSST was published by Shanghai Jiao Tong University,Shanghai AI Lab,East China University of Science and Technology, based in China, categorised as academia,Academia,Academia.

07

When was ProSST released?

ProSST was published in May 2024. Capability per parameter has improved considerably since, so a newer model of the same size is often the better use of the same hardware.

Source

Original publication

Record last updated 1 January 2026

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