eFold

Closed weights Harvard Medical School,Stanford University,Columbia University,University of Strasbourg April 2024

No estimate

No hardware requirements for this model

The weights for this model have not been published, so it cannot be downloaded or run on your own hardware at any size. It is reachable only through its provider, and no graphics card changes that.

On record

Full specification

Everything on record for this model. Most of it describes how it was trained rather than how it runs — useful context for judging how much work went into it, and how it compares with models built at a different scale.

Origin

Who built this model, where, and when it was published.

Organisation
Harvard Medical School,Stanford University,Columbia University,University of Strasbourg
Organisation type
Academia,Academia,Academia,Academia
Country
United States of America, France
Published
4 April 2024
Authors
Silvi Rouskin, Alberic de Lajart, Yves Martin des Taillades, Colin Kalicki, Federico Fuchs Wightman, Justin Aruda, Dragui Salazar, Matthew Allan, Casper L'Esperance-Kerckhoff, Alex Kashi, Fabrice Jossinet

What it does

The problem areas the model was built for. A model can carry several of each.

Domain
Biology
Task
Protein or nucleotide language model (pLM/nLM)

Size

How large the model is and how much data it was trained on. Parameters are the figure that decides whether it fits on a given graphics card.

Training data
tokens

pretraining: "over 120,000 unique sequences and structures” (bpRNA + Ribonanza); "The final dataset contains 227,000 sequences up to 512 in length." (synthetic from RNAcentral + RNAstructure Fold) finetuning: "1,456 mRNA and 1,098 pri-miRNA structures" after filtering (RNAndria)

How it is classified

Labels the source dataset applies when tracking notable models, and how confident it is in the entry.

Record confidence
Confident

Sources

Where this record came from and when it was last checked.

Reference
Diverse Database and Machine Learning Model to Narrow the Generalization Gap in RNA Structure Prediction
Last updated
28 November 2025

What the numbers mean

What this model is

eFold was published by Harvard Medical School,Stanford University,Columbia University,University of Strasbourg, in United States of America, in April 2024. academia,Academia,Academia,Academia is the category the publisher falls under.

It works in Biology, and is recorded as doing protein or nucleotide language model (pLM/nLM).

Its weights were never published, so it can only be reached through its provider. No graphics card changes that.

Answers

eFold — common questions

01

What GPU do I need to run eFold?

None. eFold is a closed model — its weights were never published, so it cannot be downloaded or run on your own hardware at any price. It is reachable only through its provider.

02

Is eFold open source?

The licensing for eFold was never recorded in our source data. We treat unstated licensing as closed, because an unrecorded licence is not one to rely on.

03

How many parameters does eFold have?

No parameter count has been published for eFold, which is why no memory or speed figure appears on this page.

04

Who created eFold?

eFold was published by Harvard Medical School,Stanford University,Columbia University,University of Strasbourg, based in United States of America, categorised as academia,Academia,Academia,Academia.

05

When was eFold released?

eFold was published in April 2024. Capability per parameter has improved considerably since, so a newer model of the same size is often the better use of the same hardware.

06

What is eFold used for?

eFold works in Biology, and is recorded as handling protein or nucleotide language model (pLM/nLM). These are the areas it was designed around; they describe intent rather than a hard boundary.

Source

Original publication

Record last updated 28 November 2025

The other direction

Looking at it from the other side?

This page starts from the model. If you already own a card and want to know everything it will run, start from the hardware instead.