AutoDiff

Closed weights Galixir Technologies,Rensselaer Polytechnic Institute,Massachusetts Institute of Technology (MIT) April 2024

No estimate

No hardware requirements for this model

The weights for this model have not been published, so it cannot be downloaded or run on your own hardware at any size. It is reachable only through its provider, and no graphics card changes that.

On record

Full specification

Everything on record for this model. Most of it describes how it was trained rather than how it runs — useful context for judging how much work went into it, and how it compares with models built at a different scale.

Origin

Who built this model, where, and when it was published.

Organisation
Galixir Technologies,Rensselaer Polytechnic Institute,Massachusetts Institute of Technology (MIT)
Organisation type
Industry,Academia,Academia
Country
China, United States of America
Published
2 April 2024
Authors
Xinze Li, Penglei Wang, Tianfan Fu, Wenhao Gao, Chengtao Li, Leilei Shi, Junhong Liu

What it does

The problem areas the model was built for. A model can carry several of each.

Domain
Biology
Task
Drug discovery

Size

How large the model is and how much data it was trained on. Parameters are the figure that decides whether it fits on a given graphics card.

Training data
tokens

22.5M poses = 22.5M datapoints = 22,500,000 datapoints Final estimate = 22.5M

Availability

Whether you can obtain the model and run it on your own hardware, which is what decides if any of the graphics-card figures on this page apply.

Weights
Closed — provider access only
Model access
Unreleased
Training code
Unreleased

How it is classified

Labels the source dataset applies when tracking notable models, and how confident it is in the entry.

Record confidence
Confident
Citations
5

Sources

Where this record came from and when it was last checked.

Reference
AUTODIFF: Autoregressive Diffusion Modeling for Structure-based Drug Design
Last updated
28 November 2025

What the numbers mean

About this model

AutoDiff was published by Galixir Technologies,Rensselaer Polytechnic Institute,Massachusetts Institute of Technology (MIT), in China, in April 2024. It comes out of industry,Academia,Academia.

It works in Biology, and is recorded as doing drug discovery.

Its weights were never published, so it can only be reached through its provider. No graphics card changes that.

Answers

AutoDiff — common questions

01

Is AutoDiff open source?

No. AutoDiff has not had its weights published, so it exists only as a service controlled by its owner.

02

How many parameters does AutoDiff have?

No parameter count has been published for AutoDiff, which is why no memory or speed figure appears on this page.

03

Who created AutoDiff?

AutoDiff was published by Galixir Technologies,Rensselaer Polytechnic Institute,Massachusetts Institute of Technology (MIT), based in China, categorised as industry,Academia,Academia.

04

When was AutoDiff released?

AutoDiff was published in April 2024. Capability per parameter has improved considerably since, so a newer model of the same size is often the better use of the same hardware.

05

What is AutoDiff used for?

AutoDiff works in Biology, and is recorded as handling drug discovery. A model can carry several of each, so these are the areas it was built for rather than a limit on what it will attempt.

06

What GPU do I need to run AutoDiff?

None. AutoDiff is a closed model — its weights were never published, so it cannot be downloaded or run on your own hardware at any price. It is reachable only through its provider.

Source

Original publication

Record last updated 28 November 2025

The other direction

Looking at it from the other side?

This page starts from the model. If you already own a card and want to know everything it will run, start from the hardware instead.