ProteinStructureTransformer

Closed weights Max Planck Institute of Biochemistry 1.1B parameters January 2024

No estimate

No hardware requirements for this model

The weights for this model have not been published, so it cannot be downloaded or run on your own hardware at any size. It is reachable only through its provider, and no graphics card changes that.

On record

Full specification

Everything on record for this model. Most of it describes how it was trained rather than how it runs — useful context for judging how much work went into it, and how it compares with models built at a different scale.

Origin

Who built this model, where, and when it was published.

Organisation
Max Planck Institute of Biochemistry
Organisation type
Academia
Country
Germany
Published
26 January 2024
Authors
Dexiong Chen, Philip Hartout, Paolo Pellizzoni, Carlos Oliver, Karsten Borgwardt

What it does

The problem areas the model was built for. A model can carry several of each.

Domain
Biology
Task
Protein or nucleotide language model (pLM/nLM)
Base model
ESM2-650M

Size

How large the model is and how much data it was trained on. Parameters are the figure that decides whether it fits on a given graphics card.

Parameters
1.1B
Training data
tokens

542,378 proteins × 300 residues/protein = 162,713,400 tokens (1.627e8) Final estimate: 1.6e8 datapoints

Epochs
100

Training compute

The arithmetic performed to train the model, measured in floating-point operations. It is a measure of what the training run cost, not of how fast the finished model answers you.

Training compute
7.6 × 10²¹ FLOP

GPU hour estimate 4*36000s*9.9e+14*0.4=5.7e+19 Base model: 7.560000000001e+21 Combined: 7616995200001001000000

How it was established
Hardware
Fine-tuning compute
5.7 × 10¹⁹ FLOP

The training run

What it physically took to train: which chips, how many, for how long, and what that drew from the wall.

Training hardware
NVIDIA H100 SXM5 80GB
Chips used
4
Wall-clock time
10 hours
Power draw
5.5 kW

How it is classified

Labels the source dataset applies when tracking notable models, and how confident it is in the entry.

Record confidence
Confident
Citations
21

Sources

Where this record came from and when it was last checked.

Reference
ENDOWING PROTEIN LANGUAGE MODELS WITH STRUCTURAL KNOWLEDGE
Last updated
25 May 2026

What the numbers mean

Background

ProteinStructureTransformer was published by Max Planck Institute of Biochemistry, in Germany, in January 2024. It comes out of academia.

It works in Biology, and is recorded as doing protein or nucleotide language model (pLM/nLM).

It is derived from ESM2-650M rather than trained from scratch, which is the usual way a specialised model is produced.

This is a closed model: the trained values stayed with whoever produced them, and there is no local version to run.

What went into building it

Producing it required around 7.6 × 10²¹ FLOP of arithmetic, on NVIDIA H100 SXM5 80GB, which is a statement about the training budget rather than about inference.

Answers

ProteinStructureTransformer — common questions

01

How many parameters does ProteinStructureTransformer have?

ProteinStructureTransformer has 1.1B parameters. That figure is the total, and it is what decides how much memory the model needs — roughly half a gigabyte per billion at the compression most people use.

02

Who created ProteinStructureTransformer?

ProteinStructureTransformer was published by Max Planck Institute of Biochemistry, based in Germany, categorised as academia.

03

When was ProteinStructureTransformer released?

ProteinStructureTransformer was published in January 2024. Capability per parameter has improved considerably since, so a newer model of the same size is often the better use of the same hardware.

04

What is ProteinStructureTransformer used for?

ProteinStructureTransformer works in Biology, and is recorded as handling protein or nucleotide language model (pLM/nLM). These are the areas it was designed around; they describe intent rather than a hard boundary.

05

How much compute was used to train ProteinStructureTransformer?

Around 7.6 × 10²¹ FLOP, on NVIDIA H100 SXM5 80GB. That measures what producing the model cost and says nothing about how quickly it answers once trained — inference speed comes from memory bandwidth, not from the training budget.

06

What GPU do I need to run ProteinStructureTransformer?

None. ProteinStructureTransformer is a closed model — its weights were never published, so it cannot be downloaded or run on your own hardware at any price. It is reachable only through its provider.

07

Is ProteinStructureTransformer open source?

The licensing for ProteinStructureTransformer was never recorded in our source data. We treat unstated licensing as closed, because an unrecorded licence is not one to rely on.

Source

Original publication

Record last updated 25 May 2026

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