Prothyena

Closed weights Tokyo Institute of Technology 4.3M parameters January 2024

No estimate

No hardware requirements for this model

The weights for this model have not been published, so it cannot be downloaded or run on your own hardware at any size. It is reachable only through its provider, and no graphics card changes that.

On record

Full specification

Everything on record for this model. Most of it describes how it was trained rather than how it runs — useful context for judging how much work went into it, and how it compares with models built at a different scale.

Origin

Who built this model, where, and when it was published.

Organisation
Tokyo Institute of Technology
Organisation type
Academia
Country
Japan
Published
22 January 2024
Authors
Yiming Zhang, Manabu Okumura

What it does

The problem areas the model was built for. A model can carry several of each.

Domain
Biology
Task
Protein or nucleotide language model (pLM/nLM)

Size

How large the model is and how much data it was trained on. Parameters are the figure that decides whether it fits on a given graphics card.

Parameters
4.3M

"This model employs a BPE tokenizer with a vocabulary size of 10k, which consequentially expands the model parameters to 4.3 million"

Training data
tokens

Data Estimate Summary: 10,000,000 sequences × 300 amino acids = 3,000,000,000 tokens (3 billion)

How it is classified

Labels the source dataset applies when tracking notable models, and how confident it is in the entry.

Record confidence
Confident
Citations
4

Sources

Where this record came from and when it was last checked.

Reference
ProtHyena: A fast and efficient foundation protein language model at single amino acid Resolution
Last updated
28 November 2025

What the numbers mean

Where it came from

Prothyena was published by Tokyo Institute of Technology, in Japan, in January 2024. academia is the category the publisher falls under.

It works in Biology, and is recorded as doing protein or nucleotide language model (pLM/nLM).

This is a closed model: the trained values stayed with whoever produced them, and there is no local version to run.

Answers

Prothyena — common questions

01

Who created Prothyena?

Prothyena was published by Tokyo Institute of Technology, based in Japan, categorised as academia.

02

When was Prothyena released?

Prothyena was published in January 2024. Capability per parameter has improved considerably since, so a newer model of the same size is often the better use of the same hardware.

03

What is Prothyena used for?

Prothyena works in Biology, and is recorded as handling protein or nucleotide language model (pLM/nLM). A model can carry several of each, so these are the areas it was built for rather than a limit on what it will attempt.

04

What GPU do I need to run Prothyena?

None. Prothyena is a closed model — its weights were never published, so it cannot be downloaded or run on your own hardware at any price. It is reachable only through its provider.

05

Is Prothyena open source?

The licensing for Prothyena was never recorded in our source data. We treat unstated licensing as closed, because an unrecorded licence is not one to rely on.

06

How many parameters does Prothyena have?

Prothyena has 4.3M parameters. "This model employs a BPE tokenizer with a vocabulary size of 10k, which consequentially expands the model parameters to 4.3 million". That figure is the total, and it is what decides how much memory the model needs — roughly half a gigabyte per billion at the compression most people use.

Source

Original publication

Record last updated 28 November 2025

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