BigRNA

Closed weights DeepGenomics 2B parameters September 2023

No estimate

No hardware requirements for this model

The weights for this model have not been published, so it cannot be downloaded or run on your own hardware at any size. It is reachable only through its provider, and no graphics card changes that.

On record

Full specification

Everything on record for this model. Most of it describes how it was trained rather than how it runs — useful context for judging how much work went into it, and how it compares with models built at a different scale.

Origin

Who built this model, where, and when it was published.

Organisation
DeepGenomics
Organisation type
Industry
Country
Canada
Published
27 September 2023
Authors
Albi Celaj, Alice Jiexin Gao, Tammy T.Y. Lau, Erle M. Holgersen, Alston Lo, Varun Lodaya, Christopher B. Cole, Robert E. Denroche, Carl Spickett, Omar Wagih, Pedro O. Pinheiro, Parth Vora, Pedrum Mohammadi-Shemirani, Steve Chan, Zach Nussbaum, Xi Zhang, Helen Zhu, Easwaran Ramamurthy, Bhargav Kanuparthi, Michael Iacocca, Diane Ly, Ken Kron, Marta Verby, Kahlin Cheung-Ong, Zvi Shalev, Brandon Vaz,…

What it does

The problem areas the model was built for. A model can carry several of each.

Domain
Biology
Task
Drug discovery, Protein-RNA binding affinity prediction, Gene expression profile generation

Size

How large the model is and how much data it was trained on. Parameters are the figure that decides whether it fits on a given graphics card.

Parameters
2B

2B

Training data
1,000,000,000,000 tokens

"trained on thousands of datasets comprising one trillion genomic signals"

Training compute

The arithmetic performed to train the model, measured in floating-point operations. It is a measure of what the training run cost, not of how fast the finished model answers you.

Training compute
1.2 × 10²² FLOP

6 FLOP/parameter/token * 2000000000 parameters * 1000000000000 tokens = 1.2e+22 FLOP "Likely" confidence because I amnot sure that "signals" correspond directly to gradient updates

How it was established
Operation counting

Availability

Whether you can obtain the model and run it on your own hardware, which is what decides if any of the graphics-card figures on this page apply.

Weights
Closed — provider access only
Model access
Unreleased
Training code
Unreleased

How it is classified

Labels the source dataset applies when tracking notable models, and how confident it is in the entry.

Record confidence
Likely

Sources

Where this record came from and when it was last checked.

Reference
An RNA foundation model enables discovery of disease mechanisms and candidate therapeutics
Last updated
28 November 2025

What the numbers mean

Where it came from

BigRNA was published by DeepGenomics, in Canada, in September 2023. industry is the category the publisher falls under.

It works in Biology, and is recorded as doing drug discovery, Protein-RNA binding affinity prediction, Gene expression profile generation.

Because the weights are not available, none of the hardware figures elsewhere on this site apply to it.

Training and provenance

Training it took roughly 1.2 × 10²² FLOP of computation — a measure of what producing the model cost, not of how fast it answers.

The training set ran to roughly 1,000,000,000,000 tokens.

Answers

BigRNA — common questions

01

How many parameters does BigRNA have?

BigRNA has 2B parameters. 2B. That figure is the total, and it is what decides how much memory the model needs — roughly half a gigabyte per billion at the compression most people use.

02

Who created BigRNA?

BigRNA was published by DeepGenomics, based in Canada, categorised as industry.

03

When was BigRNA released?

BigRNA was published in September 2023. Capability per parameter has improved considerably since, so a newer model of the same size is often the better use of the same hardware.

04

What is BigRNA used for?

BigRNA works in Biology, and is recorded as handling drug discovery, Protein-RNA binding affinity prediction, Gene expression profile generation. A model can carry several of each, so these are the areas it was built for rather than a limit on what it will attempt.

05

How much compute was used to train BigRNA?

Around 1.2 × 10²² FLOP. That measures what producing the model cost and says nothing about how quickly it answers once trained — inference speed comes from memory bandwidth, not from the training budget.

06

What GPU do I need to run BigRNA?

None. BigRNA is a closed model — its weights were never published, so it cannot be downloaded or run on your own hardware at any price. It is reachable only through its provider.

07

Is BigRNA open source?

No. BigRNA has not had its weights published, so it exists only as a service controlled by its owner.

Source

Original publication

Record last updated 28 November 2025

The other direction

Looking at it from the other side?

This page starts from the model. If you already own a card and want to know everything it will run, start from the hardware instead.