SYNTERACT

Closed weights University of Delaware 420M parameters June 2023

No estimate

No hardware requirements for this model

The weights for this model have not been published, so it cannot be downloaded or run on your own hardware at any size. It is reachable only through its provider, and no graphics card changes that.

On record

Full specification

Everything on record for this model. Most of it describes how it was trained rather than how it runs — useful context for judging how much work went into it, and how it compares with models built at a different scale.

Origin

Who built this model, where, and when it was published.

Organisation
University of Delaware
Organisation type
Academia
Country
United States of America
Published
9 June 2023
Authors
Logan Hallee, Jason P. Gleghorn

What it does

The problem areas the model was built for. A model can carry several of each.

Domain
Biology
Task
Protein interaction prediction
Base model
ProtBERT-BFD

Size

How large the model is and how much data it was trained on. Parameters are the figure that decides whether it fits on a given graphics card.

Parameters
420M
Training data
tokens

353,976 pairs × 500 avg amino acids = 176,988,000 tokens ≈ 1.8 × 10⁸ tokens {pairs calculation: 179,018 + 3,958 + 170,000 = 353,976}

Batch size
70

How it is classified

Labels the source dataset applies when tracking notable models, and how confident it is in the entry.

Record confidence
Confident

Sources

Where this record came from and when it was last checked.

Reference
Protein-Protein Interaction Prediction is Achievable with Large Language Models
Last updated
28 November 2025

What the numbers mean

Where it came from

SYNTERACT was published by University of Delaware, in the country recorded as United States of America, during June 2023. It comes out of an organisation categorised as academia.

It works in the domain of Biology, and is recorded as performing the task of protein interaction prediction.

Rather than being trained from scratch, it is derived from ProtBERT-BFD. Most models at this scale are adapted from an existing base rather than built from nothing.

Its weights were never published, so it can only be reached through its provider. No graphics card changes that.

Answers

SYNTERACT — common questions

01

SYNTERACT— who created it?

It was published by University of Delaware, based in United States of America, an organisation categorised as academia.

02

SYNTERACT— when was it released?

It was published in June 2023. Capability per parameter has improved considerably since, so a newer model of the same size is often the better use of the same hardware.

03

SYNTERACT— what is it used for?

It works in the domain of Biology, and is recorded as handling the task of protein interaction prediction. Models frequently carry more than one of each, and the tags describe purpose rather than capability limits.

04

SYNTERACT— what GPU do I need to run it?

None. This is a closed model — its weights were never published, so it cannot be downloaded or run on your own hardware at any price. It is reachable only through its provider.

05

SYNTERACT— is it open source?

The licensing was never recorded in our source data. We treat unstated licensing as closed, because an unrecorded licence is not one to rely on.

06

SYNTERACT— how many parameters does it have?

It has a parameter count of 420M. That figure is the total, and it is what decides how much memory the model needs — roughly half a gigabyte per billion at the compression most people use.

Source

Original publication

Record last updated 28 November 2025

The other direction

Looking at it from the other side?

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