OpenBioLLM-Llama3-70B TPS calculator

Open weights Saama 70B parameters January 2025

Each card below is assessed against this model at the context length and minimum quality you choose. Speed is an estimate for a single request, calculated from the card's memory bandwidth and the size of the model once compressed.

Calculated for this model

61 cards that can run it

818 cards we hold specifications for

Smallest card that fits

A100 PCIe 40 GB

40 GB · Q3_K_M · 25.5 tok/s

Fastest card

B200

48.4 tok/s · 180 GB

Which GPUs can run OpenBioLLM-Llama3-70B?

Set the inputs, read the answer

A longer conversation needs more memory, which can push this model off smaller cards.

Hides cards that would only fit the model by compressing it below this point.

61 cards match

Calculating
Needs Quantisation Fit
48.4 tok/s

41–58

B200 NVIDIA 180 GB 8,000 GB/s Jan 2024 73.8 GB Q8_0 Comfortable
48.4 tok/s

41–58

B300 NVIDIA 288 GB 8,000 GB/s Sep 2025 73.8 GB Q8_0 Comfortable
38.7 tok/s

23–62 · low confidence

Radeon Instinct MI350X AMD 288 GB 8,190 GB/s Jan 2025 73.8 GB Q8_0 Comfortable
38.7 tok/s

23–62 · low confidence

Radeon Instinct MI355X AMD 288 GB 8,190 GB/s Jan 2025 73.8 GB Q8_0 Comfortable
30.9 tok/s

19–49 · low confidence

Radeon Instinct MI300 AMD 128 GB 6,550 GB/s Jan 2023 73.8 GB Q8_0 Comfortable
29.6 tok/s

25–36

H200 NVL NVIDIA 141 GB 4,890 GB/s Nov 2024 73.8 GB Q8_0 Comfortable
29.6 tok/s

25–36

H200 SXM 141 GB NVIDIA 141 GB 4,890 GB/s Nov 2024 73.8 GB Q8_0 Comfortable
29.5 tok/s

25–35

H100 SXM5 80 GB NVIDIA 80 GB 3,360 GB/s Oct 2022 57.5 GB Q6_K Comfortable
29.5 tok/s

25–35

H800 SXM5 NVIDIA 80 GB 3,360 GB/s Mar 2023 57.5 GB Q6_K Comfortable
28.3 tok/s

17–45 · low confidence

Radeon Instinct MI325X AMD 256 GB 6,000 GB/s Oct 2024 73.8 GB Q8_0 Comfortable
26.1 tok/s

22–31

GRID A100B NVIDIA 48 GB 1,870 GB/s May 2020 41.2 GB Q4_K_M Tight
25.5 tok/s

22–31

A100 PCIe 40 GB NVIDIA 40 GB 1,560 GB/s Jun 2020 33.0 GB Q3_K_M Tight
25.5 tok/s

22–31

A100 SXM4 40 GB NVIDIA 40 GB 1,560 GB/s May 2020 33.0 GB Q3_K_M Tight
25.5 tok/s

22–31

A800 PCIe 40 GB NVIDIA 40 GB 1,560 GB/s Nov 2022 33.0 GB Q3_K_M Tight
25.1 tok/s

15–40 · low confidence

Radeon Instinct MI300A AMD 128 GB 5,325 GB/s Dec 2023 73.8 GB Q8_0 Comfortable
25.1 tok/s

15–40 · low confidence

Radeon Instinct MI300X AMD 192 GB 5,325 GB/s Dec 2023 73.8 GB Q8_0 Comfortable
25.1 tok/s

15–40 · low confidence

Radeon Instinct MI308X AMD 192 GB 5,325 GB/s Dec 2023 73.8 GB Q8_0 Comfortable
23.8 tok/s

20–29

H100 NVL 94 GB NVIDIA 94 GB 3,940 GB/s Mar 2023 73.8 GB Q8_0 Tight
20.3 tok/s

17–24

H100 PCIe 96 GB NVIDIA 96 GB 3,360 GB/s Mar 2023 73.8 GB Q8_0 Tight
20.3 tok/s

17–24

H100 SXM5 94 GB NVIDIA 94 GB 3,360 GB/s Mar 2023 73.8 GB Q8_0 Tight
20.3 tok/s

17–24

H100 SXM5 96 GB NVIDIA 96 GB 3,360 GB/s Mar 2023 73.8 GB Q8_0 Tight
18.7 tok/s

16–22

RTX PRO 5000 Blackwell NVIDIA 48 GB 1,340 GB/s Mar 2025 41.2 GB Q4_K_M Tight
17.9 tok/s

15–22

A100 SXM4 80 GB NVIDIA 80 GB 2,040 GB/s Nov 2020 57.5 GB Q6_K Comfortable
17.9 tok/s

15–22

A100X NVIDIA 80 GB 2,040 GB/s Jun 2021 57.5 GB Q6_K Comfortable
17.9 tok/s

15–22

A800 SXM4 80 GB NVIDIA 80 GB 2,040 GB/s Aug 2022 57.5 GB Q6_K Comfortable

Speeds are estimates for a single request — one conversation at a time — calculated from memory bandwidth, model size and quantisation. Real throughput varies with the inference runtime and its version. Figures published by hardware vendors measure many simultaneous requests and are much higher.

On record

Full specification

Everything on record for this model. Most of it describes how it was trained rather than how it runs — useful context for judging how much work went into it, and how it compares with models built at a different scale.

Origin

Who built this model, where, and when it was published.

Organisation
Saama
Country
United States of America
Published
14 January 2025
Authors
Ankit Pal, Malaikannan Sankarasubbu

What it does

The problem areas the model was built for. A model can carry several of each.

Domain
Language, Medicine
Task
Language modeling/generation, Question answering, Medical diagnosis
Base model
Llama 3-70B

Size

How large the model is and how much data it was trained on. Parameters are the figure that decides whether it fits on a given graphics card.

Parameters
70B

70B

Training data
tokens
Epochs
4

The training run

What it physically took to train: which chips, how many, for how long, and what that drew from the wall.

Training hardware
NVIDIA H100 SXM5 80GB
Chips used
8
Power draw
11.0 kW

Availability

Whether you can obtain the model and run it on your own hardware, which is what decides if any of the graphics-card figures on this page apply.

Weights
Open — downloadable
Model access
Open weights (restricted use)
Training code
Unreleased

Llama 3 license https://huggingface.co/aaditya/Llama3-OpenBioLLM-70B

Hugging Face
aaditya

How it is classified

Labels the source dataset applies when tracking notable models, and how confident it is in the entry.

Record confidence
Confident

Sources

Where this record came from and when it was last checked.

Reference
Introducing OpenBioLLM-Llama3-70B & 8B: Saama’s AI Research Lab Released the Most Openly Available Medical-Domain LLMs to Date!
Last updated
28 November 2025

The extremes

What the numbers mean

Hardware requirements in practice

Minimum card

A100 PCIe 40 GB

Memory needed

33.0 GB

Fastest

48.4 tok/s

OpenBioLLM-Llama3-70B sits at 70B parameters, which puts it above consumer hardware and into the range where a card is bought for this purpose rather than repurposed for it. 61 of the cards we track can hold it.

The entry point is the A100 PCIe 40 GB: 40 GB of memory, Q3_K_M compression, roughly 25.5 tokens per second.

The quickest result comes from a B200 at around 48.4 tokens per second — its 8,000 GB/s of bandwidth is what buys that.

Where it came from

OpenBioLLM-Llama3-70B was published by Saama, in United States of America, in January 2025.

It works in Language, Medicine, and is recorded as doing language modeling/generation, Question answering, Medical diagnosis.

It is derived from Llama 3-70B rather than trained from scratch, which is the usual way a specialised model is produced.

The weights are published, so it can be downloaded and run on your own hardware indefinitely, offline, with no account attached. It is published under the aaditya organisation on Hugging Face.

Understanding the speeds

Across every card that can run it, the middle of the range is about 17.1 tokens per second, and 49 of them clear the ten tokens per second that roughly matches reading speed.

Being dense, it reads all of itself per token, which is why the ordering by speed below follows the ordering by memory bandwidth so closely.

Its attention layout is on file, so the memory figures are computed exactly rather than approximated.

Step by step

How to choose a GPU for OpenBioLLM-Llama3-70B

The table above has already assessed every card we hold specifications for against this model. Getting to your answer takes six steps.

  1. 01

    Start from the memory column

    The table lists every card that can hold OpenBioLLM-Llama3-70B — around 33.0 GB at Q3_K_M. That figure, not the card's headline performance, is what decides whether it runs.

  2. 02

    Set the context length you will work at

    Longer conversations cost memory on top of what the weights need. Move the slider to your real working length before trusting any row for OpenBioLLM-Llama3-70B.

  3. 03

    Set a quality floor

    The quantisation column varies by card, because a bigger card holds a more accurate copy of OpenBioLLM-Llama3-70B — Q3_K_M on the smallest card that fits. Set a floor to hold the comparison at one level.

  4. 04

    Sort by speed

    The speed ordering for OpenBioLLM-Llama3-70B is effectively an ordering by memory bandwidth, which is why the B200 tops it at 48.4 tok/s.

  5. 05

    Check the fit verdict before buying

    The fit column separates cards that just manage OpenBioLLM-Llama3-70B from those with room to spare. Buy for the second if the context might grow.

  6. 06

    See what else that card runs

    Following a card through to its own page shows every other model it can hold, which is the question that follows once OpenBioLLM-Llama3-70B is settled.

Answers

OpenBioLLM-Llama3-70B — common questions

01

What GPU do I need to run OpenBioLLM-Llama3-70B?

The smallest card in our catalogue that holds OpenBioLLM-Llama3-70B is the A100 PCIe 40 GB, with 40 GB of memory. It runs the model at Q3_K_M using about 33.0 GB, and produces roughly 25.5 tokens per second. 61 cards in total can run it.

02

How fast is OpenBioLLM-Llama3-70B on a GPU?

It depends on the card. The quickest we calculate is a B200 at about 48.4 tokens per second; the slowest that still runs it manages considerably less. Reading speed is around ten tokens per second, and 49 of the cards that can run OpenBioLLM-Llama3-70B clear that.

03

How much VRAM does OpenBioLLM-Llama3-70B need?

About 33.0 GB at Q3_K_M compression, which is what the smallest card that runs it uses. Less compression needs more: the figures in the memory column above are recalculated for each card, because each one holds the least-compressed version it can.

04

Is OpenBioLLM-Llama3-70B open source?

Its weights are published, so OpenBioLLM-Llama3-70B can be downloaded and run on your own hardware. Note that open weights is not the same as open source in the full sense — it says nothing about the training data, the training code, or the commercial terms attached.

05

How many parameters does OpenBioLLM-Llama3-70B have?

OpenBioLLM-Llama3-70B has 70B parameters. 70B. That figure is the total, and it is what decides how much memory the model needs — roughly half a gigabyte per billion at the compression most people use.

06

Who created OpenBioLLM-Llama3-70B?

OpenBioLLM-Llama3-70B was published by Saama, based in United States of America.

07

When was OpenBioLLM-Llama3-70B released?

OpenBioLLM-Llama3-70B was published in January 2025.

08

What is OpenBioLLM-Llama3-70B used for?

OpenBioLLM-Llama3-70B works in Language, Medicine, and is recorded as handling language modeling/generation, Question answering, Medical diagnosis. These are the areas it was designed around; they describe intent rather than a hard boundary.

09

Where can I download OpenBioLLM-Llama3-70B?

Its weights are published under the aaditya organisation on Hugging Face. We do not host model files — this site calculates what hardware is needed to run them.

10

Can I run OpenBioLLM-Llama3-70B if it does not fit in my GPU?

It can be split between the card and system memory, but OpenBioLLM-Llama3-70B generates painfully slowly that way — the nearest miss we calculate is short by 12.4 GB. Nothing on this page assumes offloading.

11

Would two GPUs run OpenBioLLM-Llama3-70B faster?

Two cards buy memory rather than speed. That matters for OpenBioLLM-Llama3-70B only if one card cannot hold it — 61 can, so a second adds little.

12

Why does the quantisation differ between cards for OpenBioLLM-Llama3-70B?

Because capacity varies, so does how hard OpenBioLLM-Llama3-70B has to be squeezed — 4 distinct levels appear in the table above. Set a minimum quality to compare at one.

13

How accurate are these OpenBioLLM-Llama3-70B speed estimates?

These are estimates with real error bars. The fastest result here, 41–58 tok/s on the B200, could reasonably land anywhere in its published range depending on which runtime you use.

Source

Original publication

Record last updated 28 November 2025

The other direction

Looking at it from the other side?

This page starts from the model. If you already own a card and want to know everything it will run, start from the hardware instead.