BindCraft

Closed weights Ecole Polytechnique F´ed´erale de Lausanne (EPFL),University of Zurich,University of Lausanne,Massachusetts Institute of Technology (MIT),Visterra Inc,Swiss Federal Institute of Technology October 2024

No estimate

No hardware requirements for this model

The weights for this model have not been published, so it cannot be downloaded or run on your own hardware at any size. It is reachable only through its provider, and no graphics card changes that.

On record

Full specification

Everything on record for this model. Most of it describes how it was trained rather than how it runs — useful context for judging how much work went into it, and how it compares with models built at a different scale.

Origin

Who built this model, where, and when it was published.

Organisation
Ecole Polytechnique F´ed´erale de Lausanne (EPFL),University of Zurich,University of Lausanne,Massachusetts Institute of Technology (MIT),Visterra Inc,Swiss Federal Institute of Technology
Organisation type
Academia,Academia,Academia,Academia,Industry,Academia
Country
Switzerland, United States of America
Published
1 October 2024
Authors
Martin Pacesa, Lennart Nickel, Joseph Schmidt, Ekaterina Pyatova, Christian Schellhaas, Lucas Kissling, Ana Alcaraz-Serna, Yehlin Cho, Kourosh H. Ghamary, Laura Vinué, Brahm J. Yachnin, Andrew M. Wollacott, Stephen Buckley, Sandrine Georgeon, Casper A. Goverde, Georgios N. Hatzopoulos, Pierre Gönczy, Yannick D. Muller, Gerald Schwank, Sergey Ovchinnikov, Bruno E. Correia

What it does

The problem areas the model was built for. A model can carry several of each.

Domain
Biology
Task
Protein design
Base model
AlphaFold 2

Size

How large the model is and how much data it was trained on. Parameters are the figure that decides whether it fits on a given graphics card.

Training data
tokens

Availability

Whether you can obtain the model and run it on your own hardware, which is what decides if any of the graphics-card figures on this page apply.

Weights
Closed — provider access only
Model access
Unreleased
Training code
Open source

The full BindCraft code along with installation instructions and binder design protocols are available on GitHub under MIT license (https://github.com/martinpacesa/BindCraft). A Google Colab notebook for running BindCraft is available at https://github.com/martinpacesa/BindCraft/blob/main/notebooks/BindCraft.ipynb

How it is classified

Labels the source dataset applies when tracking notable models, and how confident it is in the entry.

Record confidence
Unknown

Sources

Where this record came from and when it was last checked.

Reference
BindCraft: one-shot design of functional protein binders
Last updated
28 November 2025

What the numbers mean

Where it came from

BindCraft was published by Ecole Polytechnique F´ed´erale de Lausanne (EPFL),University of Zurich,University of Lausanne,Massachusetts Institute of Technology (MIT),Visterra Inc,Swiss Federal Institute of Technology, in Switzerland, in October 2024. It comes out of academia,Academia,Academia,Academia,Industry,Academia.

It works in Biology, and is recorded as doing protein design.

It is derived from AlphaFold 2 rather than trained from scratch, which is the usual way a specialised model is produced.

Its weights were never published, so it can only be reached through its provider. No graphics card changes that.

Answers

BindCraft — common questions

01

Is BindCraft open source?

No. BindCraft has not had its weights published, so it exists only as a service controlled by its owner.

02

How many parameters does BindCraft have?

No parameter count has been published for BindCraft, which is why no memory or speed figure appears on this page.

03

Who created BindCraft?

BindCraft was published by Ecole Polytechnique F´ed´erale de Lausanne (EPFL),University of Zurich,University of Lausanne,Massachusetts Institute of Technology (MIT),Visterra Inc,Swiss Federal Institute of Technology, based in Switzerland, categorised as academia,Academia,Academia,Academia,Industry,Academia.

04

When was BindCraft released?

BindCraft was published in October 2024. Capability per parameter has improved considerably since, so a newer model of the same size is often the better use of the same hardware.

05

What is BindCraft used for?

BindCraft works in Biology, and is recorded as handling protein design. Models frequently carry more than one of each, and the tags describe purpose rather than capability limits.

06

What GPU do I need to run BindCraft?

None. BindCraft is a closed model — its weights were never published, so it cannot be downloaded or run on your own hardware at any price. It is reachable only through its provider.

Source

Original publication

Record last updated 28 November 2025

The other direction

Looking at it from the other side?

This page starts from the model. If you already own a card and want to know everything it will run, start from the hardware instead.