CodonMPNN

Open weights Harvard Medical School,Massachusetts Institute of Technology (MIT) September 2024

No estimate

No hardware requirements for this model

This model's weights are open, but no parameter count has been published for it. Every memory and speed figure starts from that number, so we would rather show nothing than a fabricated estimate.

On record

Full specification

Everything on record for this model. Most of it describes how it was trained rather than how it runs — useful context for judging how much work went into it, and how it compares with models built at a different scale.

Origin

Who built this model, where, and when it was published.

Organisation
Harvard Medical School,Massachusetts Institute of Technology (MIT)
Organisation type
Academia,Academia
Country
United States of America
Published
25 September 2024
Authors
Hannes Stark, Umesh Padia, Julia Balla, Cameron Diao, George Church

What it does

The problem areas the model was built for. A model can carry several of each.

Domain
Biology
Task
Codon design

Size

How large the model is and how much data it was trained on. Parameters are the figure that decides whether it fits on a given graphics card.

Training data
tokens

Availability

Whether you can obtain the model and run it on your own hardware, which is what decides if any of the graphics-card figures on this page apply.

Weights
Open — downloadable
Model access
Open weights (unrestricted)
Training code
Open source

MIT license https://github.com/HannesStark/CodonMPNN

How it is classified

Labels the source dataset applies when tracking notable models, and how confident it is in the entry.

Record confidence
Unknown

Sources

Where this record came from and when it was last checked.

Reference
CodonMPNN for Organism Specific and Codon Optimal Inverse Folding
Last updated
28 November 2025

What the numbers mean

Where it came from

CodonMPNN was published by Harvard Medical School,Massachusetts Institute of Technology (MIT), in United States of America, in September 2024. The organisation is categorised as academia,Academia.

It works in Biology, and is recorded as doing codon design.

Because its weights were released, nothing about running it depends on a provider staying available — it is yours once downloaded.

Answers

CodonMPNN — common questions

01

What GPU do I need to run CodonMPNN?

We cannot say. CodonMPNN has open weights, but no parameter count has been published for it, and every memory and speed calculation starts from that number. We would rather show nothing than a fabricated estimate.

02

Is CodonMPNN open source?

Its weights are published, so CodonMPNN can be downloaded and run on your own hardware. Note that open weights is not the same as open source in the full sense — it says nothing about the training data, the training code, or the commercial terms attached.

03

How many parameters does CodonMPNN have?

No parameter count has been published for CodonMPNN, which is why no memory or speed figure appears on this page.

04

Who created CodonMPNN?

CodonMPNN was published by Harvard Medical School,Massachusetts Institute of Technology (MIT), based in United States of America, categorised as academia,Academia.

05

When was CodonMPNN released?

CodonMPNN was published in September 2024. Capability per parameter has improved considerably since, so a newer model of the same size is often the better use of the same hardware.

06

What is CodonMPNN used for?

CodonMPNN works in Biology, and is recorded as handling codon design. These are the areas it was designed around; they describe intent rather than a hard boundary.

07

Where can I download CodonMPNN?

The weights for CodonMPNN are published, though we do not hold a repository link for it. This site calculates hardware requirements rather than hosting model files.

Source

Original publication

Record last updated 28 November 2025

The other direction

Looking at it from the other side?

This page starts from the model. If you already own a card and want to know everything it will run, start from the hardware instead.