Thermostable protein design

Closed weights Indraprastha Institute of Information Technology Delhi 738M parameters September 2024

No estimate

No hardware requirements for this model

The weights for this model have not been published, so it cannot be downloaded or run on your own hardware at any size. It is reachable only through its provider, and no graphics card changes that.

On record

Full specification

Everything on record for this model. Most of it describes how it was trained rather than how it runs — useful context for judging how much work went into it, and how it compares with models built at a different scale.

Origin

Who built this model, where, and when it was published.

Organisation
Indraprastha Institute of Information Technology Delhi
Organisation type
Academia
Country
India
Published
24 September 2024
Authors
Purva Tijare, Nishant Kumar, Gajendra P. S. Raghava

What it does

The problem areas the model was built for. A model can carry several of each.

Domain
Biology
Task
Protein design

Size

How large the model is and how much data it was trained on. Parameters are the figure that decides whether it fits on a given graphics card.

Parameters
738M

"This model comprises 36 layers and has a dimensionality of 1280, amounting to a total of 738 million parameters [28]."

Training data
tokens

"Training Dataset 13849 sequences" in Figure 1 Assumed length of 300 tokens per sequence: 13849*300

Training compute

The arithmetic performed to train the model, measured in floating-point operations. It is a measure of what the training run cost, not of how fast the finished model answers you.

Training compute
1.8 × 10¹⁶ FLOP

6*4154700*738000000=1.8397012e+16

How it was established
Operation counting

How it is classified

Labels the source dataset applies when tracking notable models, and how confident it is in the entry.

Record confidence
Confident

Sources

Where this record came from and when it was last checked.

Reference
Designing of thermostable proteins with a desired melting temperature
Last updated
28 November 2025

What the numbers mean

Background

Thermostable protein design was published by Indraprastha Institute of Information Technology Delhi, in the country recorded as India, during September 2024. The publishing organisation is categorised as academia.

It works in the domain of Biology, and is recorded as performing the task of protein design.

Its weights were never published, so it can only be reached through its provider. No graphics card changes that.

How it was trained

Producing it required arithmetic totalling around 1.8 × 10¹⁶ FLOP. That figure measures what producing the model cost, and has no bearing on how fast it answers.

Answers

Thermostable protein design — common questions

01

Thermostable protein design— who created it?

It was published by Indraprastha Institute of Information Technology Delhi, based in India, an organisation categorised as academia.

02

Thermostable protein design— when was it released?

It was published in September 2024. Capability per parameter has improved considerably since, so a newer model of the same size is often the better use of the same hardware.

03

Thermostable protein design— what is it used for?

It works in the domain of Biology, and is recorded as handling the task of protein design. These are the areas it was designed around; they describe intent rather than a hard boundary.

04

Thermostable protein design— how much compute was used to train it?

Training consumed around 1.8 × 10¹⁶ FLOP. That measures what producing the model cost and says nothing about how quickly it answers once trained — inference speed comes from memory bandwidth, not from the training budget.

05

Thermostable protein design— what GPU do I need to run it?

None. This is a closed model — its weights were never published, so it cannot be downloaded or run on your own hardware at any price. It is reachable only through its provider.

06

Thermostable protein design— is it open source?

The licensing was never recorded in our source data. We treat unstated licensing as closed, because an unrecorded licence is not one to rely on.

07

Thermostable protein design— how many parameters does it have?

It has a parameter count of 738M. "This model comprises 36 layers and has a dimensionality of 1280, amounting to a total of 738 million parameters [28].". That figure is the total, and it is what decides how much memory the model needs — roughly half a gigabyte per billion at the compression most people use.

Source

Original publication

Record last updated 28 November 2025

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