AntiFormer TPS calculator

Open weights University of Florida,Sichuan University,Shihezi University,University of Macau,University of Texas Health Science Center 24.7M parameters August 2024

Each card below is assessed against this model at the context length and minimum quality you choose. Speed is an estimate for a single request, calculated from the card's memory bandwidth and the size of the model once compressed.

Calculated for this model

818 cards that can run it

818 cards we hold specifications for

Smallest card that fits

Tesla C1080

4 GB · Q8_0 · 1,494 tok/s

Fastest card

B200

137,339 tok/s · 180 GB

Which GPUs can run AntiFormer?

Set the inputs, read the answer

Context length tokens

A longer conversation needs more memory, which can push this model off smaller cards.

Minimum quality

Hides cards that would only fit the model by compressing it below this point.

Search cards

Card memory

Also show cards that cannot run it

818 cards match

Calculating

					Needs	Quantisation	Fit
137,339 tok/s 82,403–219,742 · low confidence	B200 NVIDIA	180 GB	8,000 GB/s	Jan 2024	0.7 GB	Q8_0	Comfortable
137,339 tok/s 82,403–219,742 · low confidence	B300 NVIDIA	288 GB	8,000 GB/s	Sep 2025	0.7 GB	Q8_0	Comfortable
109,669 tok/s 65,801–175,470 · low confidence	Radeon Instinct MI350X AMD	288 GB	8,190 GB/s	Jan 2025	0.7 GB	Q8_0	Comfortable
109,669 tok/s 65,801–175,470 · low confidence	Radeon Instinct MI355X AMD	288 GB	8,190 GB/s	Jan 2025	0.7 GB	Q8_0	Comfortable
87,708 tok/s 52,625–140,333 · low confidence	Radeon Instinct MI300 AMD	128 GB	6,550 GB/s	Jan 2023	0.7 GB	Q8_0	Comfortable
83,948 tok/s 50,369–134,318 · low confidence	H200 NVL NVIDIA	141 GB	4,890 GB/s	Nov 2024	0.7 GB	Q8_0	Comfortable
83,948 tok/s 50,369–134,318 · low confidence	H200 SXM 141 GB NVIDIA	141 GB	4,890 GB/s	Nov 2024	0.7 GB	Q8_0	Comfortable
80,343 tok/s 48,206–128,549 · low confidence	Radeon Instinct MI325X AMD	256 GB	6,000 GB/s	Oct 2024	0.7 GB	Q8_0	Comfortable
71,305 tok/s 42,783–114,088 · low confidence	Radeon Instinct MI300A AMD	128 GB	5,325 GB/s	Dec 2023	0.7 GB	Q8_0	Comfortable
71,305 tok/s 42,783–114,088 · low confidence	Radeon Instinct MI300X AMD	192 GB	5,325 GB/s	Dec 2023	0.7 GB	Q8_0	Comfortable
71,305 tok/s 42,783–114,088 · low confidence	Radeon Instinct MI308X AMD	192 GB	5,325 GB/s	Dec 2023	0.7 GB	Q8_0	Comfortable
67,639 tok/s 40,584–108,223 · low confidence	H100 NVL 94 GB NVIDIA	94 GB	3,940 GB/s	Mar 2023	0.7 GB	Q8_0	Comfortable
57,682 tok/s 34,609–92,292 · low confidence	H100 PCIe 96 GB NVIDIA	96 GB	3,360 GB/s	Mar 2023	0.7 GB	Q8_0	Comfortable
57,682 tok/s 34,609–92,292 · low confidence	H100 SXM5 80 GB NVIDIA	80 GB	3,360 GB/s	Oct 2022	0.7 GB	Q8_0	Comfortable
57,682 tok/s 34,609–92,292 · low confidence	H100 SXM5 94 GB NVIDIA	94 GB	3,360 GB/s	Mar 2023	0.7 GB	Q8_0	Comfortable
57,682 tok/s 34,609–92,292 · low confidence	H100 SXM5 96 GB NVIDIA	96 GB	3,360 GB/s	Mar 2023	0.7 GB	Q8_0	Comfortable
57,682 tok/s 34,609–92,292 · low confidence	H800 SXM5 NVIDIA	80 GB	3,360 GB/s	Mar 2023	0.7 GB	Q8_0	Comfortable
43,921 tok/s 26,353–70,274 · low confidence	Radeon Instinct MI250 AMD	128 GB	3,280 GB/s	Nov 2021	0.7 GB	Q8_0	Comfortable
43,921 tok/s 26,353–70,274 · low confidence	Radeon Instinct MI250X AMD	128 GB	3,280 GB/s	Nov 2021	0.7 GB	Q8_0	Comfortable
36,601 tok/s 21,961–58,561 · low confidence	Data Center GPU Max 1550 Intel	128 GB	3,280 GB/s	Jan 2023	0.7 GB	Q8_0	Comfortable
35,820 tok/s 21,492–57,312 · low confidence	Data Center GPU Max Subsystem Intel	128 GB	3,210 GB/s	Jan 2023	0.7 GB	Q8_0	Comfortable
35,021 tok/s 21,013–56,034 · low confidence	A100 SXM4 80 GB NVIDIA	80 GB	2,040 GB/s	Nov 2020	0.7 GB	Q8_0	Comfortable
35,021 tok/s 21,013–56,034 · low confidence	A100X NVIDIA	80 GB	2,040 GB/s	Jun 2021	0.7 GB	Q8_0	Comfortable
35,021 tok/s 21,013–56,034 · low confidence	A800 SXM4 80 GB NVIDIA	80 GB	2,040 GB/s	Aug 2022	0.7 GB	Q8_0	Comfortable
35,021 tok/s 21,013–56,034 · low confidence	H100 CNX NVIDIA	80 GB	2,040 GB/s	Mar 2023	0.7 GB	Q8_0	Comfortable

Speeds are estimates for a single request — one conversation at a time — calculated from memory bandwidth, model size and quantisation. Real throughput varies with the inference runtime and its version. Figures published by hardware vendors measure many simultaneous requests and are much higher.

On record

Full specification

Everything on record for this model. Most of it describes how it was trained rather than how it runs — useful context for judging how much work went into it, and how it compares with models built at a different scale.

Origin

Who built this model, where, and when it was published.

Organisation: University of Florida,Sichuan University,Shihezi University,University of Macau,University of Texas Health Science Center
Organisation type: Academia,Academia,Academia,Academia,Academia
Country: United States of America, China, Macao
Published: 20 August 2024
Authors: Qing Wang, Yuzhou Feng, Yanfei Wang, Bo Li, Jianguo Wen, Xiaobo Zhou, Qianqian Song

What it does

The problem areas the model was built for. A model can carry several of each.

Domain: Biology
Task: Protein protein binding affinity prediction

Size

How large the model is and how much data it was trained on. Parameters are the figure that decides whether it fits on a given graphics card.

Parameters: 24.7M
Training data: tokens
Batch size: 64

Training compute

The arithmetic performed to train the model, measured in floating-point operations. It is a measure of what the training run cost, not of how fast the finished model answers you.

Training compute: 1.7 × 10¹⁸ FLOP
How it was established: Hardware

The training run

What it physically took to train: which chips, how many, for how long, and what that drew from the wall.

Training hardware: NVIDIA A100 SXM4 40 GB
Chips used: 1
Power draw: 433 W

Availability

Whether you can obtain the model and run it on your own hardware, which is what decides if any of the graphics-card figures on this page apply.

Weights: Open — downloadable
Model access: Open weights (unrestricted)
Training code: Open source

How it is classified

Labels the source dataset applies when tracking notable models, and how confident it is in the entry.

Record confidence: Confident

Sources

Where this record came from and when it was last checked.

Reference: AntiFormer: graph enhanced large language model for binding affinity prediction
Last updated: 28 November 2025

The extremes

The ten fastest GPUs that run AntiFormer

Ranked by estimated tokens per second, newest card first where speeds tie. Because generation is bound by memory bandwidth, this ordering follows bandwidth rather than any gaming benchmark.

The smallest GPUs that still run AntiFormer

The cheapest route in, by memory capacity. A tight fit runs the model but leaves nothing spare for a longer conversation.

What the numbers mean

What it takes to run this model

Minimum card

Tesla C1080

Memory needed

0.7 GB

Fastest

137,339 tok/s

AntiFormer reaches a parameter count of 24.7M. That is small enough that hardware is rarely the obstacle, including on cards several years old. The number of cards we track that can run it: 818.

The smallest card that holds it is Tesla C1080, with a memory capacity of 4 GB, running it at a compression of Q8_0 and producing around 1,494 tokens per second.

The quickest result comes from B200, generating roughly 137,339 tokens per second on the strength of a memory bandwidth of 8,000 GB/s.

About this model

AntiFormer was published by University of Florida,Sichuan University,Shihezi University,University of Macau,University of Texas Health Science Center, in the country recorded as United States of America, during August 2024. The category the publisher falls under is academia,Academia,Academia,Academia,Academia.

It works in the domain of Biology, and is recorded as performing the task of protein protein binding affinity prediction.

Because its weights were released, nothing about running it depends on a provider staying available — it is yours once downloaded.

How fast it runs, and why

The median result is around 3,856.5 tokens per second. Producing text faster than most people read it: 818 of them.

Being dense, it reads all of itself per token, which is why the ordering by speed below follows the ordering by memory bandwidth so closely.

Without the attention layout on record, the memory column is an approximation. It is close enough to choose hardware by, and least reliable at long context.

Training and provenance

The training run consumed about 1.7 × 10¹⁸ FLOP, on hardware recorded as NVIDIA A100 SXM4 40 GB. That figure measures what producing the model cost, and has no bearing on how fast it answers.

Step by step

How to choose a GPU for AntiFormer

The table above has already assessed every card we hold specifications for against this model. Getting to your answer takes six steps.

01

Check what it needs before anything else

The table lists every card able to hold AntiFormer, needing around 0.7 GB at a compression of Q8_0. Capacity is the gate — a card either holds it or it does not.
02

Match the context to your actual use

The conversation occupies memory too, and grows as it goes. Set the slider to the length you expect, because at long context a card that handles short questions easily can be dropped by AntiFormer.
03

Choose how far you will compress it

Each card runs the least-compressed copy it can hold, reaching a compression of Q8_0 on the smallest card that fits. Setting a minimum quality drops the cards that only manage it by squeezing further than you would want, and holds the comparison at one level.
04

Rank by throughput rather than spec sheet

Ranking by tokens per second follows memory bandwidth rather than core counts, for AntiFormer. It will not match a gaming ordering, because generation is bound by memory bandwidth. The card topping the list is B200, at 137,339 tok/s.
05

Read the fit column last

Tight means it loads and works with no room to raise the context later, in the case of AntiFormer. Comfortable means you can grow the context later. That difference matters more than a few tokens per second, so buy for comfortable if you expect to.
06

Open the card you have settled on

Every card name links to its own page, which runs the same calculation across the whole model catalogue. A card is usually bought for more than one model, so it is worth a look before buying for AntiFormer.

Answers

AntiFormer — common questions

AntiFormer— how fast is it on a GPU?

It depends on the card. The quickest we calculate is B200, at about 137,339 tokens per second; the slowest that still runs it manages considerably less. Reading speed is around ten tokens per second, and the number of cards clearing that: 818.

AntiFormer— how much VRAM does it need?

It needs about 0.7 GB at a compression of Q8_0, which is what the smallest card that runs it uses. Less compression needs more: the figures in the memory column above are recalculated for each card, because each one holds the least-compressed version it can.

AntiFormer— can I run it on a GPU holding 8 GB?

Yes. The card CMP 170HX 8 GB, holding 8 GB, runs it at a compression of Q8_0, using about 0.7 GB and generating roughly 25,579 tokens per second. The fit is comfortable.

AntiFormer— can I run it on a GPU holding 12 GB?

Yes. The card GeForce RTX 3080 Ti, holding 12 GB, runs it at a compression of Q8_0, using about 0.7 GB and generating roughly 15,664 tokens per second. The fit is comfortable.

AntiFormer— can I run it on a GPU holding 16 GB?

Yes. The card Tesla V100 SXM2 16 GB, holding 16 GB, runs it at a compression of Q8_0, using about 0.7 GB and generating roughly 19,399 tokens per second. The fit is comfortable.

AntiFormer— can I run it on a GPU holding 24 GB?

Yes. The card GeForce RTX 5090 D V2, holding 24 GB, runs it at a compression of Q8_0, using about 0.7 GB and generating roughly 23,004 tokens per second. The fit is comfortable.

AntiFormer— is it open source?

Its weights are published, so it can be downloaded and run on your own hardware. Note that open weights is not the same as open source in the full sense — it says nothing about the training data, the training code, or the commercial terms attached.

AntiFormer— how many parameters does it have?

It has a parameter count of 24.7M. Loaded provided model file from Zenodo page into PyTorch. That figure is the total, and it is what decides how much memory the model needs — roughly half a gigabyte per billion at the compression most people use.

AntiFormer— who created it?

It was published by University of Florida,Sichuan University,Shihezi University,University of Macau,University of Texas Health Science Center, based in United States of America, an organisation categorised as academia,Academia,Academia,Academia,Academia.

AntiFormer— when was it released?

It was published in August 2024. Capability per parameter has improved considerably since, so a newer model of the same size is often the better use of the same hardware.

AntiFormer— what is it used for?

It works in the domain of Biology, and is recorded as handling the task of protein protein binding affinity prediction. These are the areas it was designed around; they describe intent rather than a hard boundary.

AntiFormer— where can I download it?

The weights are published, though we do not hold a repository link for it. This site calculates hardware requirements rather than hosting model files.

AntiFormer— how much compute was used to train it?

Training consumed around 1.7 × 10¹⁸ FLOP, on hardware recorded as NVIDIA A100 SXM4 40 GB. That measures what producing the model cost and says nothing about how quickly it answers once trained — inference speed comes from memory bandwidth, not from the training budget.

AntiFormer— can I run it if it does not fit in my GPU?

Only by offloading, which is usually a false economy: the part held in system memory drags the whole thing down. Every figure here assumes the whole model is resident on the card.

AntiFormer— would two GPUs run it faster?

Capacity adds across cards; throughput does not. The number of cards already holding it on their own: 818. So a second card is rarely the answer here.

AntiFormer— why does the quantisation differ between cards?

A larger card holds a more accurate copy. The number of compression levels used across the cards that run it: 1. Bigger cards get the more accurate version, and the quality floor above pins the comparison to one level.

AntiFormer— how accurate are these speed estimates?

These are estimates with real error bars, and any of them could reasonably land anywhere in its published range depending on which runtime you use. The fastest result here: 82,403–219,742 tok/s on B200. The same model and card vary by thirty to fifty per cent depending on the inference software and its version.

AntiFormer— what GPU do I need to run it?

The smallest card in our catalogue that holds it is Tesla C1080, with a memory capacity of 4 GB. It runs the model at a compression of Q8_0 using about 0.7 GB, and produces roughly 1,494 tokens per second. The number of cards able to run it in total: 818.

Source

Original publication

Record last updated 28 November 2025

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