Tranception TPS calculator
Each card below is assessed against this model at the context length and minimum quality you choose. Speed is an estimate for a single request, calculated from the card's memory bandwidth and the size of the model once compressed.
Calculated for this model
818 cards we hold specifications for
Smallest card that fits
Tesla C1080
4 GB · Q8_0 · 52.7 tok/s
Fastest card
B200
4,840 tok/s · 180 GB
Which GPUs can run Tranception?
Set the inputs, read the answer
A longer conversation needs more memory, which can push this model off smaller cards.
Hides cards that would only fit the model by compressing it below this point.
818 cards match
Calculating| Needs | Quantisation | Fit | |||||
|---|---|---|---|---|---|---|---|
|
4,840
tok/s
2,904–7,745 · low confidence |
B200 NVIDIA | 180 GB | 8,000 GB/s | Jan 2024 | 1.4 GB | Q8_0 | Comfortable |
|
4,840
tok/s
2,904–7,745 · low confidence |
B300 NVIDIA | 288 GB | 8,000 GB/s | Sep 2025 | 1.4 GB | Q8_0 | Comfortable |
|
3,865
tok/s
2,319–6,184 · low confidence |
Radeon Instinct MI350X AMD | 288 GB | 8,190 GB/s | Jan 2025 | 1.4 GB | Q8_0 | Comfortable |
|
3,865
tok/s
2,319–6,184 · low confidence |
Radeon Instinct MI355X AMD | 288 GB | 8,190 GB/s | Jan 2025 | 1.4 GB | Q8_0 | Comfortable |
|
3,091
tok/s
1,855–4,946 · low confidence |
Radeon Instinct MI300 AMD | 128 GB | 6,550 GB/s | Jan 2023 | 1.4 GB | Q8_0 | Comfortable |
|
2,959
tok/s
1,775–4,734 · low confidence |
H200 NVL NVIDIA | 141 GB | 4,890 GB/s | Nov 2024 | 1.4 GB | Q8_0 | Comfortable |
|
2,959
tok/s
1,775–4,734 · low confidence |
H200 SXM 141 GB NVIDIA | 141 GB | 4,890 GB/s | Nov 2024 | 1.4 GB | Q8_0 | Comfortable |
|
2,832
tok/s
1,699–4,531 · low confidence |
Radeon Instinct MI325X AMD | 256 GB | 6,000 GB/s | Oct 2024 | 1.4 GB | Q8_0 | Comfortable |
|
2,513
tok/s
1,508–4,021 · low confidence |
Radeon Instinct MI300A AMD | 128 GB | 5,325 GB/s | Dec 2023 | 1.4 GB | Q8_0 | Comfortable |
|
2,513
tok/s
1,508–4,021 · low confidence |
Radeon Instinct MI300X AMD | 192 GB | 5,325 GB/s | Dec 2023 | 1.4 GB | Q8_0 | Comfortable |
|
2,513
tok/s
1,508–4,021 · low confidence |
Radeon Instinct MI308X AMD | 192 GB | 5,325 GB/s | Dec 2023 | 1.4 GB | Q8_0 | Comfortable |
|
2,384
tok/s
1,430–3,814 · low confidence |
H100 NVL 94 GB NVIDIA | 94 GB | 3,940 GB/s | Mar 2023 | 1.4 GB | Q8_0 | Comfortable |
|
2,033
tok/s
1,220–3,253 · low confidence |
H100 PCIe 96 GB NVIDIA | 96 GB | 3,360 GB/s | Mar 2023 | 1.4 GB | Q8_0 | Comfortable |
|
2,033
tok/s
1,220–3,253 · low confidence |
H100 SXM5 80 GB NVIDIA | 80 GB | 3,360 GB/s | Oct 2022 | 1.4 GB | Q8_0 | Comfortable |
|
2,033
tok/s
1,220–3,253 · low confidence |
H100 SXM5 94 GB NVIDIA | 94 GB | 3,360 GB/s | Mar 2023 | 1.4 GB | Q8_0 | Comfortable |
|
2,033
tok/s
1,220–3,253 · low confidence |
H100 SXM5 96 GB NVIDIA | 96 GB | 3,360 GB/s | Mar 2023 | 1.4 GB | Q8_0 | Comfortable |
|
2,033
tok/s
1,220–3,253 · low confidence |
H800 SXM5 NVIDIA | 80 GB | 3,360 GB/s | Mar 2023 | 1.4 GB | Q8_0 | Comfortable |
|
1,548
tok/s
929–2,477 · low confidence |
Radeon Instinct MI250 AMD | 128 GB | 3,280 GB/s | Nov 2021 | 1.4 GB | Q8_0 | Comfortable |
|
1,548
tok/s
929–2,477 · low confidence |
Radeon Instinct MI250X AMD | 128 GB | 3,280 GB/s | Nov 2021 | 1.4 GB | Q8_0 | Comfortable |
|
1,290
tok/s
774–2,064 · low confidence |
Data Center GPU Max 1550 Intel | 128 GB | 3,280 GB/s | Jan 2023 | 1.4 GB | Q8_0 | Comfortable |
|
1,262
tok/s
757–2,020 · low confidence |
Data Center GPU Max Subsystem Intel | 128 GB | 3,210 GB/s | Jan 2023 | 1.4 GB | Q8_0 | Comfortable |
|
1,234
tok/s
741–1,975 · low confidence |
A100 SXM4 80 GB NVIDIA | 80 GB | 2,040 GB/s | Nov 2020 | 1.4 GB | Q8_0 | Comfortable |
|
1,234
tok/s
741–1,975 · low confidence |
A100X NVIDIA | 80 GB | 2,040 GB/s | Jun 2021 | 1.4 GB | Q8_0 | Comfortable |
|
1,234
tok/s
741–1,975 · low confidence |
A800 SXM4 80 GB NVIDIA | 80 GB | 2,040 GB/s | Aug 2022 | 1.4 GB | Q8_0 | Comfortable |
|
1,234
tok/s
741–1,975 · low confidence |
H100 CNX NVIDIA | 80 GB | 2,040 GB/s | Mar 2023 | 1.4 GB | Q8_0 | Comfortable |
Speeds are estimates for a single request — one conversation at a time — calculated from memory bandwidth, model size and quantisation. Real throughput varies with the inference runtime and its version. Figures published by hardware vendors measure many simultaneous requests and are much higher.
On record
Full specification
Everything on record for this model. Most of it describes how it was trained rather than how it runs — useful context for judging how much work went into it, and how it compares with models built at a different scale.
Origin
Who built this model, where, and when it was published.
- Organisation
- University of Oxford,Harvard Medical School,Cohere
- Organisation type
- Academia,Academia,Industry
- Country
- United Kingdom of Great Britain and Northern Ireland, United States of America, Canada
- Published
- 27 May 2022
- Authors
- Pascal Notin, Mafalda Dias, Jonathan Frazer, Javier Marchena-Hurtado, Aidan Gomez, Debora S. Marks, Yarin Gal
What it does
The problem areas the model was built for. A model can carry several of each.
- Domain
- Biology
- Task
- Proteins, Protein pathogenicity prediction
- Approach
- Self-supervised learning
Size
How large the model is and how much data it was trained on. Parameters are the figure that decides whether it fits on a given graphics card.
- Parameters
- 700M
- Training data
- 48,230,400,000 tokens
"Our largest transformer model, Tranception L, has 700M parameters and is trained on UniRef100 (Suzek et al., 2014)"
Total tokens = Number of Sequences × Average Sequence Length 249,000,000 × 300 = 74,700,000,000 ≈ 7.5 × 10¹⁰ tokens
Training compute
The arithmetic performed to train the model, measured in floating-point operations. It is a measure of what the training run cost, not of how fast the finished model answers you.
- Training compute
- 7.2 × 10²¹ FLOP
- How it was established
- Hardware
Trained using 64 A100 GPUs for two weeks. 64 * 312 teraFLOP/s * 14 days * 24 hours/day * 3600 seconds/hour * 0.3 utilization (assumption) = 7.24e21
The training run
What it physically took to train: which chips, how many, for how long, and what that drew from the wall.
- Training hardware
- NVIDIA A100
- Chips used
- 64
- Chip-hours
- 21,504
- Wall-clock time
- 336 hours (14 days)
- Power draw
- 51.4 kW
- Compute cost
- $15,247
2 weeks
Availability
Whether you can obtain the model and run it on your own hardware, which is what decides if any of the graphics-card figures on this page apply.
- Weights
- Open — downloadable
- Model access
- Open weights (unrestricted)
- Training code
- Open source
- Hugging Face
- OATML-Markslab
MIT license https://github.com/OATML-Markslab/Tranception https://huggingface.co/OATML-Markslab/Tranception_Large
How it is classified
Labels the source dataset applies when tracking notable models, and how confident it is in the entry.
- Why it is tracked
- SOTA improvement
- Record confidence
- Confident
- Citations
- 243
Table 2 "We introduce Tranception, a novel transformer architecture leveraging autoregressive predictions and retrieval of homologous sequences at inference to achieve state-of-the-art fitness prediction performance. Given its markedly higher performance on multiple mutants, robustness to shallow alignments and ability to score indels, our approach offers significant gain of scope over existing approaches."
Sources
Where this record came from and when it was last checked.
- Reference
- Tranception: protein fitness prediction with autoregressive transformers and inference-time retrieval
- Last updated
- 25 May 2026
The extremes
The ten fastest GPUs that run Tranception
Ranked by estimated tokens per second, newest card first where speeds tie. Because generation is bound by memory bandwidth, this ordering follows bandwidth rather than any gaming benchmark.
- 01 B300 288 GB · 8,000 GB/s · Q8_0 4,840 tok/s
- 02 B200 180 GB · 8,000 GB/s · Q8_0 4,840 tok/s
- 03 Radeon Instinct MI350X 288 GB · 8,190 GB/s · Q8_0 3,865 tok/s
- 04 Radeon Instinct MI355X 288 GB · 8,190 GB/s · Q8_0 3,865 tok/s
- 05 Radeon Instinct MI300 128 GB · 6,550 GB/s · Q8_0 3,091 tok/s
- 06 H200 NVL 141 GB · 4,890 GB/s · Q8_0 2,959 tok/s
- 07 H200 SXM 141 GB 141 GB · 4,890 GB/s · Q8_0 2,959 tok/s
- 08 Radeon Instinct MI325X 256 GB · 6,000 GB/s · Q8_0 2,832 tok/s
- 09 Radeon Instinct MI300A 128 GB · 5,325 GB/s · Q8_0 2,513 tok/s
- 10 Radeon Instinct MI300X 192 GB · 5,325 GB/s · Q8_0 2,513 tok/s
The smallest GPUs that still run Tranception
The cheapest route in, by memory capacity. A tight fit runs the model but leaves nothing spare for a longer conversation.
- 01 GeForce RTX 4010 4 GB · needs 1.4 GB · Q8_0 · comfortable 58.1 tok/s
- 02 RTX A400 4 GB · needs 1.4 GB · Q8_0 · comfortable 58.1 tok/s
- 03 RTX 500 Mobile Ada Generation 4 GB · needs 1.4 GB · Q8_0 · comfortable 77.5 tok/s
- 04 GeForce RTX 3050 A Mobile 4 GB · needs 1.4 GB · Q8_0 · comfortable 116 tok/s
- 05 Jetson Orin Nano 4 GB 4 GB · needs 1.4 GB · Q8_0 · comfortable 20.6 tok/s
- 06 Radeon RX 6450M 4 GB · needs 1.4 GB · Q8_0 · comfortable 60.4 tok/s
- 07 Radeon RX 6550M 4 GB · needs 1.4 GB · Q8_0 · comfortable 68.0 tok/s
- 08 Radeon RX 6550S 4 GB · needs 1.4 GB · Q8_0 · comfortable 60.4 tok/s
- 09 Arc A310 4 GB · needs 1.4 GB · Q8_0 · comfortable 48.8 tok/s
- 10 Arc Pro A30M 4 GB · needs 1.4 GB · Q8_0 · comfortable 50.3 tok/s
What the numbers mean
Hardware requirements in practice
Minimum card
Tesla C1080
Memory needed
1.4 GB
Fastest
4,840 tok/s
Tranception is small enough at 700M parameters that hardware is rarely the obstacle — 818 of the cards we track can run it, including cards several years old.
The entry point is the Tesla C1080: 4 GB of memory, Q8_0 compression, roughly 52.7 tokens per second.
A B200 is the fastest we calculate for it: about 4,840 tokens per second, from 8,000 GB/s of memory bandwidth.
About this model
Tranception was published by University of Oxford,Harvard Medical School,Cohere, in United Kingdom of Great Britain and Northern Ireland, in May 2022. It comes out of academia,Academia,Industry.
It works in Biology, and is recorded as doing proteins, Protein pathogenicity prediction.
The weights are published, so it can be downloaded and run on your own hardware indefinitely, offline, with no account attached. It is published under the OATML-Markslab organisation on Hugging Face.
How fast it runs, and why
Across every card that can run it, the middle of the range is about 135.9 tokens per second, and 809 of them clear the ten tokens per second that roughly matches reading speed.
Being dense, it reads all of itself per token, which is why the ordering by speed below follows the ordering by memory bandwidth so closely.
Its internal architecture is not on file, so memory is approximated from the parameter count and marked accordingly. Expect the real figure to differ, more so at long context.
How it was trained
The training run consumed about 7.2 × 10²¹ FLOP, on NVIDIA A100. That figure describes the cost of creating it and has no bearing on how quickly it generates text.
Around 48,230,400,000 tokens went into training it.
Its inclusion criterion is sOTA improvement.
Step by step
How to choose a GPU for Tranception
The table above has already assessed every card we hold specifications for against this model. Getting to your answer takes six steps.
-
01
Read the memory figure first
The table lists every card that can hold Tranception — around 1.4 GB at Q8_0. That figure, not the card's headline performance, is what decides whether it runs.
-
02
Match the context to your actual use
The conversation occupies memory too, and grows as it goes. Set the slider to the length you expect: at long context Tranception can slip off a card that handles short questions easily.
-
03
Set a quality floor
Compression is what makes Tranception fit smaller cards, at some cost in accuracy — Q8_0 on the smallest card that fits. A minimum quality removes the ones that go too far.
-
04
Sort by speed
The speed ordering for Tranception is effectively an ordering by memory bandwidth, which is why the B200 tops it at 4,840 tok/s.
-
05
Look at the headroom, not just the fit
Tight means Tranception loads and works, with no room to raise the context later. Comfortable means you can. The difference matters more than a few tokens per second.
-
06
See what else that card runs
Every card name links to its own page, which runs the same calculation across the whole model catalogue. Worth a look before buying for Tranception alone — a card is usually bought for more than one model.
Answers
Tranception — common questions
Can I run Tranception if it does not fit in my GPU?
Partly. Layers that do not fit sit in system memory and run at a fraction of the speed, so a mostly-offloaded Tranception is rarely worth using. Every figure here assumes the whole model is on the card.
Would two GPUs run Tranception faster?
Capacity adds across cards; throughput does not. Since 818 of the cards we track already hold Tranception on their own, a second card is rarely the answer here.
Why does the quantisation differ between cards for Tranception?
A larger card holds a more accurate copy. Across the cards that run Tranception, 1 compression levels are used; the floor control above pins it to one.
How accurate are these Tranception speed estimates?
They are calculated from specifications rather than measured, and each carries a range — 2,904–7,745 tok/s on the B200, for instance. The same model and card vary by thirty to fifty per cent depending on the inference software and its version.
What GPU do I need to run Tranception?
The smallest card in our catalogue that holds Tranception is the Tesla C1080, with 4 GB of memory. It runs the model at Q8_0 using about 1.4 GB, and produces roughly 52.7 tokens per second. 818 cards in total can run it.
How fast is Tranception on a GPU?
It depends on the card. The quickest we calculate is a B200 at about 4,840 tokens per second; the slowest that still runs it manages considerably less. Reading speed is around ten tokens per second, and 809 of the cards that can run Tranception clear that.
How much VRAM does Tranception need?
About 1.4 GB at Q8_0 compression, which is what the smallest card that runs it uses. Less compression needs more: the figures in the memory column above are recalculated for each card, because each one holds the least-compressed version it can.
Can I run Tranception on a 8 GB GPU?
Yes. A CMP 170HX 8 GB with 8 GB runs it at Q8_0, using about 1.4 GB and generating roughly 902 tokens per second — a comfortable fit.
Can I run Tranception on a 12 GB GPU?
Yes. A GeForce RTX 3080 Ti with 12 GB runs it at Q8_0, using about 1.4 GB and generating roughly 552 tokens per second — a comfortable fit.
Can I run Tranception on a 16 GB GPU?
Yes. A Tesla V100 SXM2 16 GB with 16 GB runs it at Q8_0, using about 1.4 GB and generating roughly 684 tokens per second — a comfortable fit.
Can I run Tranception on a 24 GB GPU?
Yes. A GeForce RTX 5090 D V2 with 24 GB runs it at Q8_0, using about 1.4 GB and generating roughly 811 tokens per second — a comfortable fit.
Is Tranception open source?
Its weights are published, so Tranception can be downloaded and run on your own hardware. Note that open weights is not the same as open source in the full sense — it says nothing about the training data, the training code, or the commercial terms attached.
How many parameters does Tranception have?
Tranception has 700M parameters. "Our largest transformer model, Tranception L, has 700M parameters and is trained on UniRef100 (Suzek et al., 2014)". That figure is the total, and it is what decides how much memory the model needs — roughly half a gigabyte per billion at the compression most people use.
Who created Tranception?
Tranception was published by University of Oxford,Harvard Medical School,Cohere, based in United Kingdom of Great Britain and Northern Ireland, categorised as academia,Academia,Industry.
When was Tranception released?
Tranception was published in May 2022. Capability per parameter has improved considerably since, so a newer model of the same size is often the better use of the same hardware.
What is Tranception used for?
Tranception works in Biology, and is recorded as handling proteins, Protein pathogenicity prediction. Models frequently carry more than one of each, and the tags describe purpose rather than capability limits.
Where can I download Tranception?
Its weights are published under the OATML-Markslab organisation on Hugging Face. We do not host model files — this site calculates what hardware is needed to run them.
How much compute was used to train Tranception?
Around 7.2 × 10²¹ FLOP, on NVIDIA A100. That measures what producing the model cost and says nothing about how quickly it answers once trained — inference speed comes from memory bandwidth, not from the training budget.
The other direction
Looking at it from the other side?
This page starts from the model. If you already own a card and want to know everything it will run, start from the hardware instead.