Novae TPS calculator

Open weights CentraleSupelec,Gustave Roussy,Université Paris Cité 32M parameters September 2024

Each card below is assessed against this model at the context length and minimum quality you choose. Speed is an estimate for a single request, calculated from the card's memory bandwidth and the size of the model once compressed.

Calculated for this model

818 cards that can run it

818 cards we hold specifications for

Smallest card that fits

Tesla C1080

4 GB · Q8_0 · 1,152 tok/s

Fastest card

B200

105,882 tok/s · 180 GB

Which GPUs can run Novae?

Set the inputs, read the answer

Context length tokens

A longer conversation needs more memory, which can push this model off smaller cards.

Minimum quality

Hides cards that would only fit the model by compressing it below this point.

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Card memory

Also show cards that cannot run it

818 cards match

Calculating

					Needs	Quantisation	Fit
105,882 tok/s 63,529–169,412 · low confidence	B200 NVIDIA	180 GB	8,000 GB/s	Jan 2024	0.7 GB	Q8_0	Comfortable
105,882 tok/s 63,529–169,412 · low confidence	B300 NVIDIA	288 GB	8,000 GB/s	Sep 2025	0.7 GB	Q8_0	Comfortable
84,550 tok/s 50,730–135,280 · low confidence	Radeon Instinct MI350X AMD	288 GB	8,190 GB/s	Jan 2025	0.7 GB	Q8_0	Comfortable
84,550 tok/s 50,730–135,280 · low confidence	Radeon Instinct MI355X AMD	288 GB	8,190 GB/s	Jan 2025	0.7 GB	Q8_0	Comfortable
67,619 tok/s 40,571–108,191 · low confidence	Radeon Instinct MI300 AMD	128 GB	6,550 GB/s	Jan 2023	0.7 GB	Q8_0	Comfortable
64,721 tok/s 38,832–103,553 · low confidence	H200 NVL NVIDIA	141 GB	4,890 GB/s	Nov 2024	0.7 GB	Q8_0	Comfortable
64,721 tok/s 38,832–103,553 · low confidence	H200 SXM 141 GB NVIDIA	141 GB	4,890 GB/s	Nov 2024	0.7 GB	Q8_0	Comfortable
61,941 tok/s 37,165–99,106 · low confidence	Radeon Instinct MI325X AMD	256 GB	6,000 GB/s	Oct 2024	0.7 GB	Q8_0	Comfortable
54,973 tok/s 32,984–87,956 · low confidence	Radeon Instinct MI300A AMD	128 GB	5,325 GB/s	Dec 2023	0.7 GB	Q8_0	Comfortable
54,973 tok/s 32,984–87,956 · low confidence	Radeon Instinct MI300X AMD	192 GB	5,325 GB/s	Dec 2023	0.7 GB	Q8_0	Comfortable
54,973 tok/s 32,984–87,956 · low confidence	Radeon Instinct MI308X AMD	192 GB	5,325 GB/s	Dec 2023	0.7 GB	Q8_0	Comfortable
52,147 tok/s 31,288–83,435 · low confidence	H100 NVL 94 GB NVIDIA	94 GB	3,940 GB/s	Mar 2023	0.7 GB	Q8_0	Comfortable
44,471 tok/s 26,682–71,153 · low confidence	H100 PCIe 96 GB NVIDIA	96 GB	3,360 GB/s	Mar 2023	0.7 GB	Q8_0	Comfortable
44,471 tok/s 26,682–71,153 · low confidence	H100 SXM5 80 GB NVIDIA	80 GB	3,360 GB/s	Oct 2022	0.7 GB	Q8_0	Comfortable
44,471 tok/s 26,682–71,153 · low confidence	H100 SXM5 94 GB NVIDIA	94 GB	3,360 GB/s	Mar 2023	0.7 GB	Q8_0	Comfortable
44,471 tok/s 26,682–71,153 · low confidence	H100 SXM5 96 GB NVIDIA	96 GB	3,360 GB/s	Mar 2023	0.7 GB	Q8_0	Comfortable
44,471 tok/s 26,682–71,153 · low confidence	H800 SXM5 NVIDIA	80 GB	3,360 GB/s	Mar 2023	0.7 GB	Q8_0	Comfortable
33,861 tok/s 20,317–54,178 · low confidence	Radeon Instinct MI250 AMD	128 GB	3,280 GB/s	Nov 2021	0.7 GB	Q8_0	Comfortable
33,861 tok/s 20,317–54,178 · low confidence	Radeon Instinct MI250X AMD	128 GB	3,280 GB/s	Nov 2021	0.7 GB	Q8_0	Comfortable
28,218 tok/s 16,931–45,148 · low confidence	Data Center GPU Max 1550 Intel	128 GB	3,280 GB/s	Jan 2023	0.7 GB	Q8_0	Comfortable
27,615 tok/s 16,569–44,185 · low confidence	Data Center GPU Max Subsystem Intel	128 GB	3,210 GB/s	Jan 2023	0.7 GB	Q8_0	Comfortable
27,000 tok/s 16,200–43,200 · low confidence	A100 SXM4 80 GB NVIDIA	80 GB	2,040 GB/s	Nov 2020	0.7 GB	Q8_0	Comfortable
27,000 tok/s 16,200–43,200 · low confidence	A100X NVIDIA	80 GB	2,040 GB/s	Jun 2021	0.7 GB	Q8_0	Comfortable
27,000 tok/s 16,200–43,200 · low confidence	A800 SXM4 80 GB NVIDIA	80 GB	2,040 GB/s	Aug 2022	0.7 GB	Q8_0	Comfortable
27,000 tok/s 16,200–43,200 · low confidence	H100 CNX NVIDIA	80 GB	2,040 GB/s	Mar 2023	0.7 GB	Q8_0	Comfortable

Speeds are estimates for a single request — one conversation at a time — calculated from memory bandwidth, model size and quantisation. Real throughput varies with the inference runtime and its version. Figures published by hardware vendors measure many simultaneous requests and are much higher.

On record

Full specification

Everything on record for this model. Most of it describes how it was trained rather than how it runs — useful context for judging how much work went into it, and how it compares with models built at a different scale.

Origin

Who built this model, where, and when it was published.

Organisation: CentraleSupelec,Gustave Roussy,Université Paris Cité
Organisation type: Academia
Country: France
Published: 13 September 2024
Authors: Quentin Blampey, Hakim Benkirane, Nadège Bercovici, Fabrice André, Paul-Henry Cournède

What it does

The problem areas the model was built for. A model can carry several of each.

Domain: Biology
Task: Spatial Transcriptomics

Size

How large the model is and how much data it was trained on. Parameters are the figure that decides whether it fits on a given graphics card.

Parameters: 32M
Training data: tokens

Training compute

The arithmetic performed to train the model, measured in floating-point operations. It is a measure of what the training run cost, not of how fast the finished model answers you.

Training compute: 1.1 × 10¹⁹ FLOP
How it was established: Hardware

The training run

What it physically took to train: which chips, how many, for how long, and what that drew from the wall.

Training hardware: NVIDIA A100 SXM4 40 GB
Chips used: 1
Wall-clock time: 24 hours
Power draw: 433 W

Availability

Whether you can obtain the model and run it on your own hardware, which is what decides if any of the graphics-card figures on this page apply.

Weights: Open — downloadable
Model access: Open weights (non-commercial)
Training code: Open source
Hugging Face: MICS-Lab

How it is classified

Labels the source dataset applies when tracking notable models, and how confident it is in the entry.

Record confidence: Confident

Sources

Where this record came from and when it was last checked.

Reference: Novae: a graph-based foundation model for spatial transcriptomics data
Last updated: 28 November 2025

The extremes

The ten fastest GPUs that run Novae

Ranked by estimated tokens per second, newest card first where speeds tie. Because generation is bound by memory bandwidth, this ordering follows bandwidth rather than any gaming benchmark.

The smallest GPUs that still run Novae

The cheapest route in, by memory capacity. A tight fit runs the model but leaves nothing spare for a longer conversation.

What the numbers mean

Hardware requirements in practice

Minimum card

Tesla C1080

Memory needed

0.7 GB

Fastest

105,882 tok/s

Novae is small enough at 32M parameters that hardware is rarely the obstacle — 818 of the cards we track can run it, including cards several years old.

The entry point is the Tesla C1080: 4 GB of memory, Q8_0 compression, roughly 1,152 tokens per second.

The quickest result comes from a B200 at around 105,882 tokens per second — its 8,000 GB/s of bandwidth is what buys that.

Background

Novae was published by CentraleSupelec,Gustave Roussy,Université Paris Cité, in France, in September 2024. The organisation is categorised as academia.

It works in Biology, and is recorded as doing spatial Transcriptomics.

The weights are published, so it can be downloaded and run on your own hardware indefinitely, offline, with no account attached. It is published under the MICS-Lab organisation on Hugging Face.

Reading the throughput figures

Across every card that can run it, the middle of the range is about 2,973.2 tokens per second, and 818 of them clear the ten tokens per second that roughly matches reading speed.

Every weight participates in every token here, so bandwidth is the whole story: the ranking below is effectively a ranking of memory throughput.

Without the attention layout on record, the memory column is an approximation. It is close enough to choose hardware by, and least reliable at long context.

Training and provenance

Training it took roughly 1.1 × 10¹⁹ FLOP of computation, on NVIDIA A100 SXM4 40 GB — a measure of what producing the model cost, not of how fast it answers.

Step by step

How to choose a GPU for Novae

The table above has already assessed every card we hold specifications for against this model. Getting to your answer takes six steps.

01

Check what it needs before anything else

The table lists every card that can hold Novae — around 0.7 GB at Q8_0. That figure, not the card's headline performance, is what decides whether it runs.
02

Decide how long your conversations run

Set the context to what you will actually use. The cache grows with the conversation, and it is the usual reason Novae stops fitting a card that seemed fine.
03

Decide how much compression you will accept

The quantisation column varies by card, because a bigger card holds a more accurate copy of Novae — Q8_0 on the smallest card that fits. Set a floor to hold the comparison at one level.
04

Compare tokens per second, not specifications

Sort by speed to see how cards rank for Novae. It will not match a gaming ordering — generation is bound by memory bandwidth, which is why the B200 tops it at 105,882 tok/s.
05

Look at the headroom, not just the fit

A tight fit runs Novae but leaves nothing spare for a longer conversation; comfortable has headroom. If you expect to grow the context, buy for comfortable.
06

Open the card you have settled on

Every card name links to its own page, which runs the same calculation across the whole model catalogue. Worth a look before buying for Novae alone — a card is usually bought for more than one model.

Answers

Novae — common questions

Can I run Novae on a 12 GB GPU?

Yes. A GeForce RTX 3080 Ti with 12 GB runs it at Q8_0, using about 0.7 GB and generating roughly 12,076 tokens per second — a comfortable fit.

Can I run Novae on a 16 GB GPU?

Yes. A Tesla V100 SXM2 16 GB with 16 GB runs it at Q8_0, using about 0.7 GB and generating roughly 14,956 tokens per second — a comfortable fit.

Can I run Novae on a 24 GB GPU?

Yes. A GeForce RTX 5090 D V2 with 24 GB runs it at Q8_0, using about 0.7 GB and generating roughly 17,735 tokens per second — a comfortable fit.

Is Novae open source?

Its weights are published, so Novae can be downloaded and run on your own hardware. Note that open weights is not the same as open source in the full sense — it says nothing about the training data, the training code, or the commercial terms attached.

How many parameters does Novae have?

Novae has 32M parameters. 32M (safetensors). That figure is the total, and it is what decides how much memory the model needs — roughly half a gigabyte per billion at the compression most people use.

Who created Novae?

Novae was published by CentraleSupelec,Gustave Roussy,Université Paris Cité, based in France, categorised as academia.

When was Novae released?

Novae was published in September 2024. Capability per parameter has improved considerably since, so a newer model of the same size is often the better use of the same hardware.

What is Novae used for?

Novae works in Biology, and is recorded as handling spatial Transcriptomics. A model can carry several of each, so these are the areas it was built for rather than a limit on what it will attempt.

Where can I download Novae?

Its weights are published under the MICS-Lab organisation on Hugging Face. We do not host model files — this site calculates what hardware is needed to run them.

How much compute was used to train Novae?

Around 1.1 × 10¹⁹ FLOP, on NVIDIA A100 SXM4 40 GB. That measures what producing the model cost and says nothing about how quickly it answers once trained — inference speed comes from memory bandwidth, not from the training budget.

Can I run Novae if it does not fit in my GPU?

Only by offloading, which is usually a false economy: the part in system memory drags the whole thing down. Our figures for Novae assume it is fully resident.

Would two GPUs run Novae faster?

Capacity adds across cards; throughput does not. Since 818 of the cards we track already hold Novae on their own, a second card is rarely the answer here.

Why does the quantisation differ between cards for Novae?

Each card is shown running the least-compressed copy it can hold, and Novae appears at 1 different compression levels across the cards that fit it. Bigger cards get the more accurate version.

How accurate are these Novae speed estimates?

Every figure is derived from memory bandwidth and model size, not benchmarked. That is why each is published as a range such as 63,529–169,412 tok/s on the B200 rather than a single number.

What GPU do I need to run Novae?

The smallest card in our catalogue that holds Novae is the Tesla C1080, with 4 GB of memory. It runs the model at Q8_0 using about 0.7 GB, and produces roughly 1,152 tokens per second. 818 cards in total can run it.

How fast is Novae on a GPU?

It depends on the card. The quickest we calculate is a B200 at about 105,882 tokens per second; the slowest that still runs it manages considerably less. Reading speed is around ten tokens per second, and 818 of the cards that can run Novae clear that.

How much VRAM does Novae need?

About 0.7 GB at Q8_0 compression, which is what the smallest card that runs it uses. Less compression needs more: the figures in the memory column above are recalculated for each card, because each one holds the least-compressed version it can.

Can I run Novae on a 8 GB GPU?

Yes. A CMP 170HX 8 GB with 8 GB runs it at Q8_0, using about 0.7 GB and generating roughly 19,721 tokens per second — a comfortable fit.

Source

Original publication

Record last updated 28 November 2025

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