MedGemma 27B TPS calculator

Open weights Google 27B parameters May 2025

Each card below is assessed against this model at the context length and minimum quality you choose. Speed is an estimate for a single request, calculated from the card's memory bandwidth and the size of the model once compressed.

Calculated for this model

241 cards that can run it

818 cards we hold specifications for

Smallest card that fits

Xeon Phi 7120P

16 GB · Q3_K_M · 9.7 tok/s

Fastest card

B200

125 tok/s · 180 GB

Which GPUs can run MedGemma 27B?

Set the inputs, read the answer

Context length tokens

A longer conversation needs more memory, which can push this model off smaller cards.

Minimum quality

Hides cards that would only fit the model by compressing it below this point.

Search cards

Card memory

Also show cards that cannot run it

241 cards match

Calculating

					Needs	Quantisation	Fit
125 tok/s 75–201 · low confidence	B200 NVIDIA	180 GB	8,000 GB/s	Jan 2024	29.6 GB	Q8_0	Comfortable
125 tok/s 75–201 · low confidence	B300 NVIDIA	288 GB	8,000 GB/s	Sep 2025	29.6 GB	Q8_0	Comfortable
100 tok/s 60–160 · low confidence	Radeon Instinct MI350X AMD	288 GB	8,190 GB/s	Jan 2025	29.6 GB	Q8_0	Comfortable
100 tok/s 60–160 · low confidence	Radeon Instinct MI355X AMD	288 GB	8,190 GB/s	Jan 2025	29.6 GB	Q8_0	Comfortable
80.1 tok/s 48–128 · low confidence	Radeon Instinct MI300 AMD	128 GB	6,550 GB/s	Jan 2023	29.6 GB	Q8_0	Comfortable
76.7 tok/s 46–123 · low confidence	H200 NVL NVIDIA	141 GB	4,890 GB/s	Nov 2024	29.6 GB	Q8_0	Comfortable
76.7 tok/s 46–123 · low confidence	H200 SXM 141 GB NVIDIA	141 GB	4,890 GB/s	Nov 2024	29.6 GB	Q8_0	Comfortable
73.4 tok/s 44–117 · low confidence	Radeon Instinct MI325X AMD	256 GB	6,000 GB/s	Oct 2024	29.6 GB	Q8_0	Comfortable
65.2 tok/s 39–104 · low confidence	Radeon Instinct MI300A AMD	128 GB	5,325 GB/s	Dec 2023	29.6 GB	Q8_0	Comfortable
65.2 tok/s 39–104 · low confidence	Radeon Instinct MI300X AMD	192 GB	5,325 GB/s	Dec 2023	29.6 GB	Q8_0	Comfortable
65.2 tok/s 39–104 · low confidence	Radeon Instinct MI308X AMD	192 GB	5,325 GB/s	Dec 2023	29.6 GB	Q8_0	Comfortable
61.8 tok/s 37–99 · low confidence	H100 NVL 94 GB NVIDIA	94 GB	3,940 GB/s	Mar 2023	29.6 GB	Q8_0	Comfortable
52.7 tok/s 32–84 · low confidence	H100 PCIe 96 GB NVIDIA	96 GB	3,360 GB/s	Mar 2023	29.6 GB	Q8_0	Comfortable
52.7 tok/s 32–84 · low confidence	H100 SXM5 80 GB NVIDIA	80 GB	3,360 GB/s	Oct 2022	29.6 GB	Q8_0	Comfortable
52.7 tok/s 32–84 · low confidence	H100 SXM5 94 GB NVIDIA	94 GB	3,360 GB/s	Mar 2023	29.6 GB	Q8_0	Comfortable
52.7 tok/s 32–84 · low confidence	H100 SXM5 96 GB NVIDIA	96 GB	3,360 GB/s	Mar 2023	29.6 GB	Q8_0	Comfortable
52.7 tok/s 32–84 · low confidence	H800 SXM5 NVIDIA	80 GB	3,360 GB/s	Mar 2023	29.6 GB	Q8_0	Comfortable
47.8 tok/s 29–77 · low confidence	Tesla V100 SXM2 16 GB NVIDIA	16 GB	1,130 GB/s	Nov 2019	13.9 GB	Q3_K_M	Tight
42.6 tok/s 26–68 · low confidence	DRIVE A100 PROD NVIDIA	32 GB	1,870 GB/s	May 2020	23.3 GB	Q6_K	Comfortable
42.6 tok/s 26–68 · low confidence	GRID A100A NVIDIA	32 GB	1,870 GB/s	May 2020	23.3 GB	Q6_K	Comfortable
40.8 tok/s 24–65 · low confidence	GeForce RTX 5090 NVIDIA	32 GB	1,790 GB/s	Jan 2025	23.3 GB	Q6_K	Comfortable
40.8 tok/s 24–65 · low confidence	GeForce RTX 5090 D NVIDIA	32 GB	1,790 GB/s	Jan 2025	23.3 GB	Q6_K	Comfortable
40.6 tok/s 24–65 · low confidence	GeForce RTX 5080 NVIDIA	16 GB	960 GB/s	Jan 2025	13.9 GB	Q3_K_M	Tight
40.1 tok/s 24–64 · low confidence	Radeon Instinct MI250 AMD	128 GB	3,280 GB/s	Nov 2021	29.6 GB	Q8_0	Comfortable
40.1 tok/s 24–64 · low confidence	Radeon Instinct MI250X AMD	128 GB	3,280 GB/s	Nov 2021	29.6 GB	Q8_0	Comfortable

Speeds are estimates for a single request — one conversation at a time — calculated from memory bandwidth, model size and quantisation. Real throughput varies with the inference runtime and its version. Figures published by hardware vendors measure many simultaneous requests and are much higher.

On record

Full specification

Everything on record for this model. Most of it describes how it was trained rather than how it runs — useful context for judging how much work went into it, and how it compares with models built at a different scale.

Origin

Who built this model, where, and when it was published.

Organisation: Google
Organisation type: Industry
Country: United States of America
Published: 20 May 2025
Authors: Andrew Sellergren, Sahar Kazemzadeh, Tiam Jaroensri, Atilla Kiraly, Madeleine Traverse, Timo Kohlberger, Shawn Xu, Fayaz Jamil, Cían Hughes, Charles Lau, Justin Chen, Fereshteh Mahvar, Liron Yatziv, Tiffany Chen, Bram Sterling, Stefanie Anna Baby, Susanna Maria Baby, Jeremy Lai, Samuel Schmidgall, Lu Yang, Kejia Chen, Per Bjornsson, Shashir Reddy, Ryan Brush, Kenneth Philbrick, Mercy Asiedu, Ines …

What it does

The problem areas the model was built for. A model can carry several of each.

Domain: Medicine, Language, Vision, Multimodal
Task: Question answering, Language modeling/generation, Medical diagnosis, Visual question answering, Image classification
Base model: Gemma 3 27B,MedSigLIP

Size

How large the model is and how much data it was trained on. Parameters are the figure that decides whether it fits on a given graphics card.

Parameters: 27B
Training data: tokens

Availability

Whether you can obtain the model and run it on your own hardware, which is what decides if any of the graphics-card figures on this page apply.

Weights: Open — downloadable
Model access: Open weights (restricted use)
Training code: Unreleased
Hugging Face: google

How it is classified

Labels the source dataset applies when tracking notable models, and how confident it is in the entry.

Record confidence: Confident

Sources

Where this record came from and when it was last checked.

Reference: MedGemma Technical Report
Last updated: 28 November 2025

The extremes

The ten fastest GPUs that run MedGemma 27B

Ranked by estimated tokens per second, newest card first where speeds tie. Because generation is bound by memory bandwidth, this ordering follows bandwidth rather than any gaming benchmark.

The smallest GPUs that still run MedGemma 27B

The cheapest route in, by memory capacity. A tight fit runs the model but leaves nothing spare for a longer conversation.

What the numbers mean

Hardware requirements in practice

Minimum card

Xeon Phi 7120P

Memory needed

13.9 GB

Fastest

125 tok/s

MedGemma 27B reaches a parameter count of 27B. That lands in the range a serious desktop card can handle once the weights are compressed. The number of cards we track that can run it: 241.

The entry point is Xeon Phi 7120P, with a memory capacity of 16 GB, running it at a compression of Q3_K_M and producing around 9.7 tokens per second.

The fastest we calculate for it is B200, generating roughly 125 tokens per second on the strength of a memory bandwidth of 8,000 GB/s.

About this model

MedGemma 27B was published by Google, in the country recorded as United States of America, during May 2025. The publishing organisation is categorised as industry.

It works in the domain of Medicine, Language, Vision, Multimodal, and is recorded as performing the task of question answering, Language modeling/generation, Medical diagnosis, Visual question answering, Image classification.

Its starting point was an existing base model, Gemma 3 27B,MedSigLIP. That is the usual way a specialised model is produced.

The weights are published, so it can be downloaded and run on your own hardware indefinitely, offline, with no account attached. On Hugging Face it is published under the organisation google.

How fast it runs, and why

Across every card that can run it, the middle of the range sits at 19.0 tokens per second. Clearing the ten tokens per second that roughly matches reading speed: 196 of them.

It is a dense model, so every parameter is read for every token produced. That makes speed track memory bandwidth almost exactly — a card with twice the bandwidth generates roughly twice as fast.

Memory here is estimated from size rather than computed from the architecture, which is not recorded for this model — the numbers are indicative rather than exact.

Step by step

How to choose a GPU for MedGemma 27B

The table above has already assessed every card we hold specifications for against this model. Getting to your answer takes six steps.

01

Start from the memory column

Every card here has been checked against MedGemma 27B, needing around 13.9 GB at a compression of Q3_K_M. No amount of processing power compensates for a card that cannot hold it.
02

Decide how long your conversations run

Longer conversations cost memory on top of what the weights need. Move the slider to your real working length before trusting any row for MedGemma 27B.
03

Set a quality floor

Compression is what makes a model fit smaller cards, at some cost in accuracy, reaching a compression of Q3_K_M on the smallest card that fits. Setting a minimum quality drops the cards that only manage it by squeezing further than you would want, and holds the comparison at one level.
04

Compare tokens per second, not specifications

Ranking by tokens per second follows memory bandwidth rather than core counts, for MedGemma 27B. It will not match a gaming ordering, because generation is bound by memory bandwidth. The card topping the list is B200, at 125 tok/s.
05

Check the fit verdict before buying

A tight fit runs, but leaves nothing spare for a longer conversation, in the case of MedGemma 27B. Comfortable means you can grow the context later. That difference matters more than a few tokens per second, so buy for comfortable if you expect to.
06

Open the card you have settled on

Following a card through to its own page shows every other model it can hold, which is the question that follows once you have settled on MedGemma 27B.

Answers

MedGemma 27B — common questions

MedGemma 27B— can I run it on a GPU holding 24 GB?

Yes. The card GeForce RTX 5090 D V2, holding 24 GB, runs it at a compression of Q5_K_M, using about 20.2 GB and generating roughly 37.5 tokens per second. The fit is tight.

MedGemma 27B— is it open source?

Its weights are published, so it can be downloaded and run on your own hardware. Note that open weights is not the same as open source in the full sense — it says nothing about the training data, the training code, or the commercial terms attached.

MedGemma 27B— how many parameters does it have?

It has a parameter count of 27B. 27B. That figure is the total, and it is what decides how much memory the model needs — roughly half a gigabyte per billion at the compression most people use.

MedGemma 27B— who created it?

It was published by Google, based in United States of America, an organisation categorised as industry.

MedGemma 27B— when was it released?

It was published in May 2025.

MedGemma 27B— what is it used for?

It works in the domain of Medicine, Language, Vision, Multimodal, and is recorded as handling the task of question answering, Language modeling/generation, Medical diagnosis, Visual question answering, Image classification. Models frequently carry more than one of each, and the tags describe purpose rather than capability limits.

MedGemma 27B— where can I download it?

Its weights are published on Hugging Face, under the organisation google. We do not host model files — this site calculates what hardware is needed to run them.

MedGemma 27B— can I run it if it does not fit in my GPU?

Only by offloading, which is usually a false economy: the part held in system memory drags the whole thing down. The nearest miss we calculate falls short by 6.2 GB. Every figure here assumes the whole model is resident on the card.

MedGemma 27B— would two GPUs run it faster?

Two cards buy memory rather than speed, which matters only if one card cannot hold it. The number that can: 241. So a second card is rarely the answer here.

MedGemma 27B— why does the quantisation differ between cards?

Each card is shown running the least-compressed copy it can hold. The number of distinct compression levels across the cards that fit it: 5. Bigger cards get the more accurate version, and the quality floor above pins the comparison to one level.

MedGemma 27B— how accurate are these speed estimates?

These are estimates with real error bars, and any of them could reasonably land anywhere in its published range depending on which runtime you use. The fastest result here: 75–201 tok/s on B200. The same model and card vary by thirty to fifty per cent depending on the inference software and its version.

MedGemma 27B— what GPU do I need to run it?

The smallest card in our catalogue that holds it is Xeon Phi 7120P, with a memory capacity of 16 GB. It runs the model at a compression of Q3_K_M using about 13.9 GB, and produces roughly 9.7 tokens per second. The number of cards able to run it in total: 241.

MedGemma 27B— how fast is it on a GPU?

It depends on the card. The quickest we calculate is B200, at about 125 tokens per second; the slowest that still runs it manages considerably less. Reading speed is around ten tokens per second, and the number of cards clearing that: 196.

MedGemma 27B— how much VRAM does it need?

It needs about 13.9 GB at a compression of Q3_K_M, which is what the smallest card that runs it uses. Less compression needs more: the figures in the memory column above are recalculated for each card, because each one holds the least-compressed version it can.

MedGemma 27B— can I run it on a GPU holding 16 GB?

Yes. The card Tesla V100 SXM2 16 GB, holding 16 GB, runs it at a compression of Q3_K_M, using about 13.9 GB and generating roughly 47.8 tokens per second. The fit is tight.

Source

Original publication

Record last updated 28 November 2025

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